Domenichini F, Querzoli G, Cenedese A, Pedrizzetti G
Dipartimento di Ingegneria Civile, University of Firenze, Italy.
J Biomech. 2007;40(9):1988-94. doi: 10.1016/j.jbiomech.2006.09.024. Epub 2006 Nov 13.
Fluid dynamics is used for diagnosis in cardiology only to a partial extent. Indeed several aspects of cardiac flows and their relation with pathophysiology are unknown. The flow that develops into the left ventricle is here studied by using a combination of numerical and experimental models. The former allows a detailed three-dimensional analysis, the latter can be used in conditions, like in presence of turbulence, that are out of reach of the current computational power. The three-dimensional flow dynamics is analyzed in terms of its vortical structure. The study, within its limitations, provides further physical understanding about the intraventricular flow structure. This could eventually support the development of cardiac diagnostic indicators based on fluid dynamics.
流体动力学在心脏病学诊断中的应用仅处于部分程度。实际上,心脏血流的几个方面及其与病理生理学的关系尚不清楚。本文通过结合数值模型和实验模型来研究流入左心室的血流。前者允许进行详细的三维分析,后者可用于当前计算能力无法触及的情况,如存在湍流的情况。从其涡旋结构方面分析三维流动动力学。该研究在其局限性内,提供了关于心室内流动结构的进一步物理理解。这最终可能支持基于流体动力学的心脏诊断指标的发展。