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格拉斯哥动脉瘤评分可预测有症状的未破裂腹主动脉瘤急诊开放修复术后的结局。

Glasgow aneurysm score predicts the outcome after emergency open repair of symptomatic, unruptured abdominal aortic aneurysms.

作者信息

Antonello M, Lepidi S, Kechagias A, Frigatti P, Tripepi A, Biancari F, Deriu G P, Grego F

机构信息

Department of Cardiac, Thoracic and Vascular Sciences, Vascular Surgery Section, Padua University Hospital, Italy.

出版信息

Eur J Vasc Endovasc Surg. 2007 Mar;33(3):272-6. doi: 10.1016/j.ejvs.2006.09.006. Epub 2006 Nov 9.

Abstract

OBJECTIVE

To determine the predictor factors of in-hospital postoperative mortality in patients presenting with symptomatic but not ruptured abdominal aortic aneurysm (AAA) at our institution.

PATIENTS AND METHODS

Forty-two patients who underwent urgent open repair for symptomatic, non-ruptured AAA were evaluated retrospectively.

RESULTS

Five patients (11.9%) died during the in-hospital stay. History of coronary artery disease (p=0.014), cerebrovascular diseases (p=0.015), renal failure according to Glasgow Aneurysm Score (GAS) criteria (p=0.001), serum creatinine concentration (p=0.026), and the GAS (p=0.008) were predictive of postoperative death. The ROC curve analysis showed that the Glasgow Aneurysm Score had an area under the curve of 0.870 (95%C.I. 0.71-1, S.E. 0.08, p=0.008), and its best cut-off value in predicting postoperative death was 90.0 (specificity 89.2%, sensitivity 80.0%). The postoperative mortality rate of patients with a Glasgow Aneurysm Score below 90 was 2.9%, whereas it was 50% for those with a score >or=90 (p=0.003, O.R. 33.0).

CONCLUSION

This study shows that the Glasgow Aneurysm Score is a good predictor of postoperative mortality and morbidity after urgent repair of symptomatic, non-ruptured AAA and can be useful in identifying those patients whose operative risk is prohibitive. Its simplicity makes it a clinically important tool, particularly, in the emergency setting. Patients having a score less than 90 can safely undergo urgent open repair. Thorough evaluation and improvement of preoperative status followed preferably by an endovascular repair is indicated for those with a score >or=90.

摘要

目的

确定在我院因有症状但未破裂的腹主动脉瘤(AAA)就诊患者术后院内死亡的预测因素。

患者与方法

对42例因有症状、未破裂的AAA接受急诊开放修复手术的患者进行回顾性评估。

结果

5例患者(11.9%)在住院期间死亡。冠状动脉疾病史(p = 0.014)、脑血管疾病史(p = 0.015)、根据格拉斯哥动脉瘤评分(GAS)标准的肾衰竭(p = 0.001)、血清肌酐浓度(p = 0.026)以及GAS(p = 0.008)可预测术后死亡。ROC曲线分析显示,格拉斯哥动脉瘤评分的曲线下面积为0.870(95%置信区间0.71 - 1,标准误0.08,p = 0.008),其预测术后死亡的最佳截断值为90.0(特异性89.2%,敏感性80.0%)。格拉斯哥动脉瘤评分低于90分的患者术后死亡率为2.9%,而评分≥90分的患者术后死亡率为50%(p = 0.003,比值比33.0)。

结论

本研究表明,格拉斯哥动脉瘤评分是有症状、未破裂AAA急诊修复术后死亡和发病的良好预测指标,有助于识别手术风险极高的患者。其简单性使其成为临床重要工具,尤其是在急诊情况下。评分低于90分的患者可安全地接受急诊开放修复手术。对于评分≥90分的患者,建议进行全面评估并改善术前状态,优先选择血管内修复。

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