Antonello M, Lepidi S, Kechagias A, Frigatti P, Tripepi A, Biancari F, Deriu G P, Grego F
Department of Cardiac, Thoracic and Vascular Sciences, Vascular Surgery Section, Padua University Hospital, Italy.
Eur J Vasc Endovasc Surg. 2007 Mar;33(3):272-6. doi: 10.1016/j.ejvs.2006.09.006. Epub 2006 Nov 9.
To determine the predictor factors of in-hospital postoperative mortality in patients presenting with symptomatic but not ruptured abdominal aortic aneurysm (AAA) at our institution.
Forty-two patients who underwent urgent open repair for symptomatic, non-ruptured AAA were evaluated retrospectively.
Five patients (11.9%) died during the in-hospital stay. History of coronary artery disease (p=0.014), cerebrovascular diseases (p=0.015), renal failure according to Glasgow Aneurysm Score (GAS) criteria (p=0.001), serum creatinine concentration (p=0.026), and the GAS (p=0.008) were predictive of postoperative death. The ROC curve analysis showed that the Glasgow Aneurysm Score had an area under the curve of 0.870 (95%C.I. 0.71-1, S.E. 0.08, p=0.008), and its best cut-off value in predicting postoperative death was 90.0 (specificity 89.2%, sensitivity 80.0%). The postoperative mortality rate of patients with a Glasgow Aneurysm Score below 90 was 2.9%, whereas it was 50% for those with a score >or=90 (p=0.003, O.R. 33.0).
This study shows that the Glasgow Aneurysm Score is a good predictor of postoperative mortality and morbidity after urgent repair of symptomatic, non-ruptured AAA and can be useful in identifying those patients whose operative risk is prohibitive. Its simplicity makes it a clinically important tool, particularly, in the emergency setting. Patients having a score less than 90 can safely undergo urgent open repair. Thorough evaluation and improvement of preoperative status followed preferably by an endovascular repair is indicated for those with a score >or=90.
确定在我院因有症状但未破裂的腹主动脉瘤(AAA)就诊患者术后院内死亡的预测因素。
对42例因有症状、未破裂的AAA接受急诊开放修复手术的患者进行回顾性评估。
5例患者(11.9%)在住院期间死亡。冠状动脉疾病史(p = 0.014)、脑血管疾病史(p = 0.015)、根据格拉斯哥动脉瘤评分(GAS)标准的肾衰竭(p = 0.001)、血清肌酐浓度(p = 0.026)以及GAS(p = 0.008)可预测术后死亡。ROC曲线分析显示,格拉斯哥动脉瘤评分的曲线下面积为0.870(95%置信区间0.71 - 1,标准误0.08,p = 0.008),其预测术后死亡的最佳截断值为90.0(特异性89.2%,敏感性80.0%)。格拉斯哥动脉瘤评分低于90分的患者术后死亡率为2.9%,而评分≥90分的患者术后死亡率为50%(p = 0.003,比值比33.0)。
本研究表明,格拉斯哥动脉瘤评分是有症状、未破裂AAA急诊修复术后死亡和发病的良好预测指标,有助于识别手术风险极高的患者。其简单性使其成为临床重要工具,尤其是在急诊情况下。评分低于90分的患者可安全地接受急诊开放修复手术。对于评分≥90分的患者,建议进行全面评估并改善术前状态,优先选择血管内修复。