从加甘岩风（Thapsia garganica）中分离出的细胞毒性苯丙素类化合物及另一种毒胡萝卜素类似物。
Cytotoxic phenylpropanoids and an additional thapsigargin analogue isolated from Thapsia garganica.
作者信息
Liu Huizhen, Jensen Kent Gunnertoft, Tran Linh My, Chen Ming, Zhai Lin, Olsen Carl Erik, Søhoel Helmer, Denmeade Samuel R, Isaacs John T, Christensen S Brøgger
机构信息
Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, Universitetsparken 2, DK-2100 Copenhagen Ø, Denmark.
出版信息
Phytochemistry. 2006 Dec;67(24):2651-8. doi: 10.1016/j.phytochem.2006.10.005. Epub 2006 Nov 13.
Four phenylpropanoids and a thapsigargin analogue have been isolated from the fruits of Thapsia garganica. A spectroscopic method for elucidating the relative stereochemistry at the two pairs of stereogenic centers in the phenylpropanoids has been developed. The phenylpropanoids were found to be potent cytotoxins.
从加甘岩风（Thapsia garganica）的果实中分离出了四种苯丙素类化合物和一种毒胡萝卜素类似物。已开发出一种光谱方法来阐明苯丙素类化合物中两对立体中心的相对立体化学结构。发现这些苯丙素类化合物是强效细胞毒素。
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