Zeiner Michaela, Ovari Mihaly, Zaray Gyula, Steffan Ilse
Department of Analytical and Food Chemistry, University of Vienna, Währingerstrasse 38, A-1090 Vienna, Austria.
J Trace Elem Med Biol. 2006;20(4):240-4. doi: 10.1016/j.jtemb.2006.07.001. Epub 2006 Aug 30.
Reference concentrations of metals are the basis for risk assessment studies and for estimation of type and magnitude of environmental and occupational exposure. Urine is often used as a specimen for monitoring studies, as it plays an important role in the elimination of various substances from the body and in addition it can be collected easily. Therefore, the urinary levels of seven trace elements (Al, Co, Cr, Mo, Nb, Ni, Ti) were determined by atomic spectrometric methods (ICP-MS and GFAAS) in 100 urine samples of the Viennese population. The obtained creatinine adjusted concentrations (medians) are in microg/g 6.1, 1.5, 1.1, 46.2, 0.4, 0.1, and 8.0 for Al, Co, Cr, Mo, Nb, Ni, and Ti, respectively.
金属的参考浓度是风险评估研究以及估算环境和职业暴露类型及程度的基础。尿液常被用作监测研究的样本，因为它在人体排出各种物质的过程中发挥着重要作用，而且易于采集。因此，采用原子光谱法（电感耦合等离子体质谱法和石墨炉原子吸收光谱法）测定了维也纳人群100份尿液样本中七种微量元素（铝、钴、铬、钼、铌、镍、钛）的尿中含量。所得到的经肌酐校正后的浓度（中位数），铝、钴、铬、钼、铌、镍和钛分别为6.1、1.5、1.1、46.2、0.4、0.1和8.0微克/克。
