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跨物种的GacA控制假单胞菌中抗菌作用的诱导。

Cross-species GacA-controlled induction of antibiosis in pseudomonads.

作者信息

Dubuis Christophe, Haas Dieter

机构信息

Département de Microbiologie Fondamentale, Université de Lausanne, CH-1015 Lausanne, Switzerland.

出版信息

Appl Environ Microbiol. 2007 Jan;73(2):650-4. doi: 10.1128/AEM.01681-06. Epub 2006 Nov 10.

DOI:10.1128/AEM.01681-06
PMID:17098922
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1796963/
Abstract

Signal extracts prepared from culture supernatants of Pseudomonas fluorescens CHA0 and Pseudomonas aeruginosa PAO stimulated GacA-dependent expression of small RNAs and hence of antibiotic compounds in both hosts. Pseudomonas corrugata LMG2172 and P. fluorescens SBW25 also produced signal molecules stimulating GacA-controlled antibiotic synthesis in strain CHA0, illustrating a novel, N-acyl-homoserine lactone-independent type of interspecies communication.

摘要

从荧光假单胞菌CHA0和铜绿假单胞菌PAO的培养上清液中制备的信号提取物，刺激了两种宿主中小RNA的GacA依赖性表达，进而刺激了抗生素化合物的表达。皱缩假单胞菌LMG2172和荧光假单胞菌SBW25也产生信号分子，刺激CHA0菌株中GacA控制的抗生素合成，这说明了一种新型的、不依赖N-酰基高丝氨酸内酯的种间通讯方式。

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本文引用的文献

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Two GacA-dependent small RNAs modulate the quorum-sensing response in Pseudomonas aeruginosa.两种依赖GacA的小RNA调节铜绿假单胞菌的群体感应反应。
J Bacteriol. 2006 Aug;188(16):6026-33. doi: 10.1128/JB.00409-06.
2
Autoinducer 2: a concentration-dependent signal for mutualistic bacterial biofilm growth.自诱导物2：互利共生细菌生物膜生长的浓度依赖性信号
Mol Microbiol. 2006 Jun;60(6):1446-56. doi: 10.1111/j.1365-2958.2006.05202.x.
3
Bacterially speaking.从细菌的角度来说。
Cell. 2006 Apr 21;125(2):237-46. doi: 10.1016/j.cell.2006.04.001.
4
Thiamine-auxotrophic mutants of Pseudomonas fluorescens CHA0 are defective in cell-cell signaling and biocontrol factor expression.荧光假单胞菌CHA0的硫胺素营养缺陷型突变体在细胞间信号传导和生物防治因子表达方面存在缺陷。
Appl Environ Microbiol. 2006 Apr;72(4):2606-13. doi: 10.1128/AEM.72.4.2606-2613.2006.
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4-quinolone signalling in Pseudomonas aeruginosa: old molecules, new perspectives.铜绿假单胞菌中的4-喹诺酮信号传导：旧分子，新视角。
Int J Med Microbiol. 2006 Apr;296(2-3):83-91. doi: 10.1016/j.ijmm.2006.01.038. Epub 2006 Feb 17.
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