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[列日精神病护理网络中精神分裂症患者的一年随访及活动能力评估]

[One-year follow-up and mobility assessment of schizophrenic patients in the Liege psychiatric care network].

作者信息

Sarto D, Desseilles M, Martin M, Seidel L, Albert A

机构信息

Psychologue, Plate-forme psychiatrique liégeoise, quai des Ardennes n 24, B-4020 Liège, Belgique.

出版信息

Encephale. 2006 Oct;32(5 Pt 1):722-8. doi: 10.1016/s0013-7006(06)76224-8.

Abstract

OBJECTIVE

The study was aimed at assessing the clinical evolution and mobility of schizophrenic patients within the healthcare network of the Psychiatric Platform of Liege (Belgium) after a one-year follow-up period.

MATERIAL AND METHODS

The study material consisted of a random sample of 184 patients with schizophrenia drawn from the population of schizophrenic patients treated in the Liege psychiatric care network. The characteristics of these patients have been described previously (18). The 184 patients were followed-up for one-year and reassessed at the end of this period. Mobility (ie, changes between psychiatric care institutions, including home) was recorded for each patient within the institutional network. The diagnosis of schizophrenia was based on the DSM IV. Demographic, social and global functioning (GAF scale) data were collected from the "Résumé psychiatrique Minimum (RPM)", a clinical summary which has been imposed by the Belgian Ministry of Public Health for each psychiatric hospital stay. Symptom components were derived from the Psychosis Evaluation tool for Common Use by Caregivers (PECC).

RESULTS

Among the 184 patients enrolled in the initial analysis, 6 refused to participate in the follow-up study. The 178 remaining schizophrenic patients included 131 men (74%) and 47 women (26%) with a mean age of 43.1 +/- 13.6 and 48.8 +/- 14.9 years, respectively (p<0.05). The majority of patients (53%) suffered from paranoid schizophrenia. At baseline, 63% of the patients were hospitalised full-time, 6% part-time and 31% received ambulatory care. During the one-year follow-up period, 4 patients died, including one from suicide. When considering mobility, 48% of the patients experienced at least one change of institution, whereas 52% of the patients didn't change at all (see figure 1). The total number of changes over the 1-year period amounted 189, yielding a mean value of 1.1 changes per patient per year. Changes mostly occurred between institutions of similar care setting (see figure 2). Transfers (30%) were also observed directly between hospital and home. A multivariate Poisson regression analysis showed that the number of changes was unrelated to gender and initial care setting but decreased with age (p<0.0001). It was also higher for patients with schizo-affective disorders (2.5 +/- 1.9, p<0.01) or with residual type (1.2 +/- 1.8; p<0.05) than for patients with other types of schizophrenia (ranging from 0.3 +/- 0.5 to 0.9 +/- 1.4). No association was found with initial GAF or PECC, except for negative symptoms (p<0.05). After one year, despite the high proportion of institutional changes (48% of the patients), the distribution of the patients according to care setting remained the same (p=0.77). However, GAF scores significantly improved from 39.7 +/- 16.1 to 44.4 +/- 16.1 (p<0.0001) and likewise for total PECC scores (70 +/- 19.1 vs 63.2 +/- 19.4, p<0.001). Excitatory and disease perception items of the PECC remained unchanged.

CONCLUSION

The present study reveals that mobility within the institutional network did affect about half of the schizophrenic patients. Mobility was related to age, type of schizophrenia and disease evolution. Changes occur mainly between psychiatric structures of similar care setting but also directly from hospital to home without passing through an intermediate care structure. Further efforts should be made to provide schizophrenic patients with a more coordinated care provision throughout the course of their disease.

摘要

目的

本研究旨在评估在为期一年的随访期后,比利时列日精神病学平台医疗网络内精神分裂症患者的临床进展和流动性。

材料与方法

研究材料包括从列日精神病护理网络中接受治疗的精神分裂症患者群体中随机抽取的184例患者。这些患者的特征已在之前进行过描述(参考文献18)。对这184例患者进行了为期一年的随访,并在随访期结束时重新进行评估。记录了机构网络内每位患者的流动性(即精神科护理机构之间的变动,包括回家)。精神分裂症的诊断依据《精神疾病诊断与统计手册第四版》(DSM-IV)。人口统计学、社会和整体功能(大体功能评定量表,GAF)数据从“最低限度精神病学摘要(RPM)”中收集,这是一份临床摘要,由比利时公共卫生部要求在每次精神病院住院时填写。症状成分源自护理人员常用的精神病评估工具(PECC)。

结果

在纳入初始分析的184例患者中,6例拒绝参与随访研究。其余178例精神分裂症患者包括131例男性(74%)和47例女性(26%),平均年龄分别为43.1±13.6岁和48.8±14.9岁(p<0.05)。大多数患者(53%)患有偏执型精神分裂症。基线时,63%的患者为全日制住院,6%为非全日制住院,31%接受门诊护理。在为期一年的随访期内,4例患者死亡,其中1例死于自杀。考虑到流动性,48%的患者经历了至少一次机构变动,而52%的患者根本没有变动(见图1)。一年期间变动的总数为189次,平均每位患者每年变动1.1次。变动大多发生在护理设置相似的机构之间(见图2)。也观察到有30%的患者直接在医院和家之间进行了转移。多变量泊松回归分析显示,变动次数与性别和初始护理设置无关,但随年龄增长而减少(p<0.0001)。患有精神分裂症伴情感障碍的患者(2.5±1.9,p<0.01)或残留型患者(1.2±1.8;p<0.05)的变动次数也高于其他类型精神分裂症患者(范围从0.3±0.5至0.9±1.4)。除了阴性症状(p<0.05)外,未发现与初始GAF或PECC有相关性。一年后,尽管机构变动的比例较高(48%的患者),但根据护理设置划分的患者分布保持不变(p = 0.77)。然而,GAF评分从39.7±16.1显著提高到44.4±16.1(p<0.0001),PECC总分也同样如此(70±19.1对63.2±19.4,p<0.001)。PECC的兴奋性和疾病感知项目保持不变。

结论

本研究表明,机构网络内的流动性确实影响了约一半的精神分裂症患者。流动性与年龄、精神分裂症类型和疾病进展有关。变动主要发生在护理设置相似的精神科机构之间,但也有患者直接从医院回家,而未经过中间护理机构。应进一步努力为精神分裂症患者在其疾病全过程中提供更协调的护理服务。

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