Ulmer S, Braga T A, Barker F G, Lev M H, Gonzalez R G, Henson J W
Stephen E. Catherine Pappas Center for Neuro-oncology and Division of Neuroradiology, Massachusetts General Hospital, Boston, MA 02114, USA.
Neurology. 2006 Nov 14;67(9):1668-70. doi: 10.1212/01.wnl.0000242894.21705.3c.
Focal areas of restricted diffusion adjacent to high-grade glioma resection cavities were detected in 70% of patients on immediate postoperative MRI studies. Follow-up studies demonstrated cystic encephalomalacia in 91% of these foci, suggesting the presence of infarction, and the infarcted tissue demonstrated enhancement in 43% of cases. New postoperative deficits correlated well with the anatomic region of infarction in six patients. Enhancement in perioperative infarcts can mimic tumor progression on follow-up imaging studies.
在术后即刻的MRI研究中，70%的患者在高级别胶质瘤切除腔附近检测到扩散受限的局灶性区域。随访研究显示，这些病灶中有91%出现囊性脑软化，提示存在梗死，并且梗死组织在43%的病例中表现出强化。6例患者术后出现的新功能缺损与梗死的解剖区域密切相关。围手术期梗死灶的强化在随访影像研究中可模拟肿瘤进展。
