Chang Y C, Nagasue N, Abe S, Kohno H, Kumar D D, Nakamura T
Second Department of Surgery, Shimane Medical University, Izumo, Japan.
Gut. 1991 May;32(5):542-5. doi: 10.1136/gut.32.5.542.
Three cases of alpha fetoprotein producing early gastric cancer are presented. Liver metastases occurred in all patients shortly after curative gastrectomy and all died within two years. The incidence of liver metastasis was significantly higher than that in alpha fetoprotein negative early gastric carcinoma (p less than 0.001). The incidences of lymph node metastasis and invasion in lymph vessels and veins were also substantially higher in this group of patients. Two radical hepatic resections, including extended right lobectomy, were performed on one patient but the tumour recurred immediately.
本文报告了3例产生甲胎蛋白的早期胃癌病例。所有患者在根治性胃切除术后不久均发生肝转移，且均在两年内死亡。肝转移的发生率显著高于甲胎蛋白阴性的早期胃癌（p<0.001）。该组患者的淋巴结转移以及淋巴管和静脉侵犯的发生率也明显更高。对1例患者进行了两次根治性肝切除术，包括扩大右叶切除术，但肿瘤立即复发。
