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73岁及以上黑人和白人中开角型青光眼的患病率:索尔兹伯里眼科评估青光眼研究

The prevalence of open-angle glaucoma among blacks and whites 73 years and older: the Salisbury Eye Evaluation Glaucoma Study.

作者信息

Friedman David S, Jampel Henry D, Muñoz Beatriz, West Sheila K

机构信息

Dana Center for Preventive Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

出版信息

Arch Ophthalmol. 2006 Nov;124(11):1625-30. doi: 10.1001/archopht.124.11.1625.


DOI:10.1001/archopht.124.11.1625
PMID:17102012
Abstract

OBJECTIVE: To determine the prevalence of glaucoma among black and white persons 73 years and older. DESIGN: Participants in the fourth round of a population-based study, the Salisbury Eye Evaluation, were examined. The main outcome measure was glaucoma, based on optic nerve damage and visual field loss or obvious glaucomatous optic neuropathy without an available, reliable, reproducible visual field. RESULTS: A total of 1250 individuals (95.9% of those eligible) participated, 1233 (98.6%) of whom agreed to screening and an eye examination. The prevalence (95% confidence interval) of open-angle glaucoma was 3.4% (0.5%-6.4%) for white individuals aged 73 and 74 years, increasing to 9.4% (7.4%-11.5%) for those 75 years and older. There was no increasing prevalence in those older than 75 years. Among black persons, the prevalence (95% confidence interval) was 5.7% (0%-11.9%) in those aged 73 and 74 years and 23.2% (17.8%-28.5%) in those 75 years and older. CONCLUSIONS: Many older individuals have open-angle glaucoma, and black persons 75 years and older have substantially higher rates than whites. These findings have important implications for public health initiatives, in which screening programs may be of benefit.

摘要

目的:确定73岁及以上黑人和白人中青光眼的患病率。 设计:对基于人群的研究——索尔兹伯里眼科评估的第四轮参与者进行检查。主要结局指标为青光眼,基于视神经损伤和视野缺损,或存在明显的青光眼性视神经病变但无可用、可靠、可重复的视野检查结果。 结果:共有1250人(占符合条件者的95.9%)参与,其中1233人(98.6%)同意进行筛查和眼部检查。73岁和74岁白人开角型青光眼的患病率(95%置信区间)为3.4%(0.5%-6.4%),75岁及以上者增至9.4%(7.4%-11.5%)。75岁以上人群的患病率没有上升。在黑人中,73岁和74岁者的患病率(95%置信区间)为5.7%(0%-11.9%),75岁及以上者为23.2%(17.8%-28.5%)。 结论:许多老年人患有开角型青光眼,75岁及以上黑人的患病率明显高于白人。这些发现对公共卫生倡议具有重要意义,筛查项目可能会从中受益。

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