Peterson I M, Raible M
Department of Pathology, Truman Medical Center/Affiliated Hospital, University of Missouri-Kansas City School of Medicine.
Acta Cytol. 1991 May-Jun;35(3):300-5.
The cytologic and histopathologic findings in a patient with Hodgkin's lymphoma, mixed cellularity type, and a malignant pleural effusion are presented. The consistency of staining with a battery of immunoperoxidase monoclonal antibody stains, including leukocyte common antigen, Leu-M1, UCHL1 and L26, was examined on sections of formalin-fixed lymph nodes and alcohol-fixed pleural fluid cell blocks. In addition, these same tissues were stained with carcinoembryonic antigen, B72.3, cytokeratin and epithelial membrane antigen immunoperoxidase antibodies to differentiate the tumor cells from reactive mesothelial cells and adenocarcinoma cells. The results on the pleural fluid specimens were consistent with what is known of the immunohistochemical staining properties of Hodgkin's lymphoma cells in lymph nodes.
本文报告了1例混合细胞型霍奇金淋巴瘤合并恶性胸腔积液患者的细胞学和组织病理学检查结果。我们在福尔马林固定的淋巴结切片和酒精固定的胸腔积液细胞块上，检测了一系列免疫过氧化物酶单克隆抗体染色的一致性，这些抗体包括白细胞共同抗原、Leu-M1、UCHL1和L26。此外，还用癌胚抗原、B72.3、细胞角蛋白和上皮膜抗原免疫过氧化物酶抗体对这些相同组织进行染色，以将肿瘤细胞与反应性间皮细胞和腺癌细胞区分开来。胸腔积液标本的检测结果与已知的淋巴结中霍奇金淋巴瘤细胞的免疫组化染色特性相符。
