Kurt Yavuz, Demirbas Sezai, Uluutku Ahmet Haldun, Akin Mehmet Levhi, Celenk Tuncay
Department of General Surgery, Gulhane Military Medical Academy, Haydarpasa Training Hospital, Kadikoy, Istanbul, Turkey.
Eur J Cancer Prev. 2006 Dec;15(6):480-2. doi: 10.1097/01.cej.0000198898.47926.8b.
Poland's syndrome, a rare congenital anomaly characterized by pectoralis muscle defect and ipsilateral hand abnormalities, has been reported in association with various malignancies. Gastric cancer associated with Poland's syndrome has not been described previously. To our knowledge, the case of the 21-year-old man we describe herein represents the first report of Poland's syndrome associated with gastric cancer. Although previously there was no certain evidence that linked Poland's syndrome and cancer, elucidating the molecular mechanisms that cause this syndrome may further clarify the relationship between Poland's syndrome and malignancies. At least, these associations confirm the relationship between Poland's syndrome and malignancies, and require oncologic awareness.
波兰综合征是一种罕见的先天性异常，其特征为胸肌缺损和同侧手部畸形，已报道与多种恶性肿瘤相关。此前尚未描述过与波兰综合征相关的胃癌。据我们所知，我们在此描述的这名21岁男性病例是波兰综合征合并胃癌的首例报道。尽管此前没有确凿证据将波兰综合征与癌症联系起来，但阐明导致该综合征的分子机制可能会进一步明确波兰综合征与恶性肿瘤之间的关系。至少，这些关联证实了波兰综合征与恶性肿瘤之间的关系，需要肿瘤学方面的关注。
