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大隐静脉移植介入治疗中的栓子保护装置

Embolic protection devices in saphenous vein graft interventions.

作者信息

Cragun David T, Heuser Richard R

机构信息

Division of Cardiology, University of Arizona, Phoenix, Arizona, USA.

出版信息

J Interv Cardiol. 2006 Dec;19(6):525-9. doi: 10.1111/j.1540-8183.2006.00204.x.

Abstract

Saphenous vein grafts (SVGs) are widely used as aortocoronary conduits during coronary artery bypass surgery and are critical in the high early success of coronary bypass revascularization. Saphenous vein grafts tend to be more prone than native coronary arteries to accelerated atherosclerosis and intimal fibrosis and thus frequently lead to recurrent symptoms and require further revascularization. Percutaneous coronary interventions (PCI) have become the prime means of SVG mechanical revascularization but are plagued by higher complication rates than PCI on native coronaries, largely due to embolic debris mobilized from around the target lesion in the SVG. Several mechanical devices and techniques have been developed to capture this friable material during the PCI before it can embolize; these devices have shown great promise in reducing the morbidity and mortality of these interventions and should be employed routinely.

摘要

大隐静脉移植物(SVGs)在冠状动脉旁路移植手术中被广泛用作主动脉冠状动脉管道,对于冠状动脉旁路血管重建术的早期高成功率至关重要。与天然冠状动脉相比,大隐静脉移植物更容易发生加速动脉粥样硬化和内膜纤维化,因此经常导致复发症状并需要进一步的血管重建。经皮冠状动脉介入治疗(PCI)已成为大隐静脉移植物机械性血管重建的主要手段,但与天然冠状动脉的PCI相比,其并发症发生率更高,这主要是由于从大隐静脉移植物的靶病变周围动员的栓塞碎片所致。已经开发了几种机械装置和技术,以在PCI期间捕获这种易碎物质,使其在栓塞之前被捕获;这些装置在降低这些干预措施的发病率和死亡率方面显示出巨大的前景,应该常规使用。

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