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心外膜脂肪组织和脂肪细胞因子水平对内脏肥胖中心脏异常的影响。

Influence of epicardial adipose tissue and adipocytokine levels on cardiac abnormalities in visceral obesity.

作者信息

Malavazos Alexis E, Ermetici Federica, Coman Calin, Corsi Massimiliano M, Morricone Lelio, Ambrosi Bruno

出版信息

Int J Cardiol. 2007 Sep 14;121(1):132-4. doi: 10.1016/j.ijcard.2006.08.061. Epub 2006 Nov 13.

DOI:10.1016/j.ijcard.2006.08.061
PMID:17107724
Abstract

Adipocytokine levels and visceral adipose tissue (VAT) seem to be associated with some cardiac abnormalities and a role of visceral fat in predisposing to cardiac dysfunction, possibly through a low-grade state of inflammation, has been demonstrated. In this study we firstly show that elevated levels of both monocyte chemoattractant protein 1 (MCP-1) and soluble IL-6 receptor/interleukin-6 (sIL-6R/IL-6) complex are closely correlated with epicardial fat thickness.

摘要

脂肪细胞因子水平和内脏脂肪组织（VAT）似乎与一些心脏异常有关，并且已经证实内脏脂肪可能通过低度炎症状态在易患心脏功能障碍方面起作用。在本研究中，我们首先表明，单核细胞趋化蛋白1（MCP-1）和可溶性IL-6受体/白细胞介素-6（sIL-6R/IL-6）复合物水平的升高与心外膜脂肪厚度密切相关。

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Influence of epicardial adipose tissue and adipocytokine levels on cardiac abnormalities in visceral obesity.心外膜脂肪组织和脂肪细胞因子水平对内脏肥胖中心脏异常的影响。
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