Burwell R G, Aujla R K, Freeman B J C, Dangerfield P H, Cole A A, Kirby A S, Pratt R K, Webb J K, Moulton A
The Centre for Spinal Studies and Surgery, Queen's Medical Centre, Nottingham, UK.
Stud Health Technol Inform. 2006;123:57-65.
Extra-spinal skeletal length asymmetry have been reported for the upper limbs and periapical ribs of patients with thoracic adolescent idiopathic scoliosis. This paper reports (1) a third pattern with relative lengthening of the ilium on the concavity of lower spine scolioses, and (2) a fourth pattern of relative lengthening of the right total leg and right tibia unrelated statistically to the severity or side of lower spinal scolioses. The findings pose the question: are these anomalous extra-spinal left-right skeletal length asymmetries unconnected with the pathogenesis of AIS. Or, are they indicative of what may also be happening to some vertebral physes as an initiating pathogenic mechanism for the scoliosis?
已有报道称,青少年特发性脊柱侧弯患者的上肢和根尖肋骨存在脊柱外骨骼长度不对称的情况。本文报道了:(1)第三种模式,即下脊柱侧弯凹侧的髂骨相对延长;(2)第四种模式,即右下肢和右胫骨相对延长,且在统计学上与下脊柱侧弯的严重程度或侧弯方向无关。这些发现引发了一个问题:这些异常的脊柱外左右骨骼长度不对称与特发性脊柱侧弯的发病机制是否无关?或者,它们是否表明某些椎体生长板也可能发生了同样的情况,从而成为脊柱侧弯的起始致病机制?