Brunetaud J M, Maunoury V, Cochelard D, Boniface B, Cortot A, Paris J C
Centre Multidisciplinaire de Traitement par Laser, Hôpital C. Huriez, Lille, France.
Acta Gastroenterol Belg. 1990 Jul-Aug;53(4):430-45.
Over a 10 year period, 530 patients were treated at the Lille Laser Center for a rectosigmoid tumour. Both argon and Nd:YAG lasers were used. Two hundred patients were treated for palliation of symptoms from a rectosigmoid cancer, 313 patients were treated for a rectosigmoid villous adenoma, and 17 patients with a familial polyposis were treated for the rectal polyposis remaining after total colectomy. The immediate success rate and complication rate were 88% and 2.7%, respectively, for patients with advanced cancer, 92% and 2% for those with a villous adenoma, and 100% and 0% for those with polyposis. Patients with an advanced cancer remained functionally improved during a 10.1 month average period after initial improvement. The recurrence rate after initial treatment for villous adenomas was 14% during a 3.1 year average follow-up. Immediate results were influenced by reason for treatment, initial symptoms and circumferential extension for patients with a cancer, and only by circumferential extension for patients with a villous adenoma. Long term results were influenced by reason for treatment and circumferential extension for patients with a cancer, and by reason for treatment, initial histology and localization for patients with a villous adenoma.
在10年期间，里尔激光中心对530例直肠乙状结肠肿瘤患者进行了治疗。使用了氩激光和钕:钇铝石榴石激光。200例患者因直肠乙状结肠癌症状缓解而接受治疗，313例患者因直肠乙状结肠绒毛状腺瘤接受治疗，17例家族性息肉病患者在全结肠切除术后因直肠息肉接受治疗。晚期癌症患者的即刻成功率和并发症发生率分别为88%和2.7%，绒毛状腺瘤患者为92%和2%，息肉病患者为100%和0%。晚期癌症患者在初次改善后的平均10.1个月期间功能持续改善。绒毛状腺瘤初次治疗后的复发率在平均3.1年的随访期间为14%。癌症患者的即刻结果受治疗原因、初始症状和肿瘤周径扩展影响，绒毛状腺瘤患者仅受肿瘤周径扩展影响。癌症患者的长期结果受治疗原因和肿瘤周径扩展影响，绒毛状腺瘤患者的长期结果受治疗原因、初始组织学和肿瘤位置影响。
