Brunetaud J M, Maunoury V, Cochelard D, Boniface B, Cortot A, Paris J C
Multidiciplinary Laser Center, Regional Hospital, Lille, France.
Lasers Surg Med. 1989;9(2):169-73. doi: 10.1002/lsm.1900090213.
Ninety-nine nonsurgical patients (group I) with esophagogastric cancer were referred to the laser center for palliation of dysphagia, and another 142 nonsurgical patients (group II) with a rectosigmoid cancer were referred for palliation of abnormal rectal discharge (125 patients) or occlusion (17 patients). The immediate success rate was 83% in group I and 90% in group II. Patients were retreated monthly. The average duration of palliation was 4.3 months +/- 0.5 (+/- standard error) in group I and 9.3 months +/- 0.95 in group II. Complication rate was 4% in group I and 3.4% in group II. Parameters affecting results were found only in group I. Factors that could negatively affect the immediate success rate included annular size of the tumor basis more than two thirds of the circumference, tumor localization at the upper third of the esophagus, and recurrence after a nonlaser treatment. The average duration of improvement after initial success was affected only by the circumferential extension.
99例非手术治疗的食管癌患者（第一组）被转至激光中心以缓解吞咽困难，另有142例非手术治疗的直肠乙状结肠癌患者（第二组）因异常直肠排出物（125例患者）或梗阻（17例患者）而被转至激光中心进行姑息治疗。第一组的即刻成功率为83%，第二组为90%。患者每月接受一次再治疗。第一组姑息治疗的平均持续时间为4.3个月±0.5（±标准误），第二组为9.3个月±0.95。第一组的并发症发生率为4%，第二组为3.4%。仅在第一组中发现了影响治疗结果的参数。可能对即刻成功率产生负面影响的因素包括肿瘤基底的环形大小超过周长的三分之二、肿瘤位于食管上三分之一处以及非激光治疗后的复发。初次成功后改善的平均持续时间仅受圆周扩展的影响。
