Ruiz Daniela Maria Cury Ferreira, Pontes Paulo, Behlau Mara, Richieri-Costa A
Departamento de Genética Clínica, Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru, SP, Brazil.
Folia Phoniatr Logop. 2006;58(6):392-9. doi: 10.1159/000095000.
The etiology and pathogenesis of laryngeal microwebs are heterogeneous, and in most cases they are an incidental finding. It has also been suggested that microwebs could be a familial trait, representing a postblastogenic embryonic vestigial structure that might alter the biomechanical and vibratory properties of the vocal fold. Vocal nodules are small benign swellings along the margins of the vocal cords, with preferential location at the junction of the anterior and middle thirds, and usually resulting from mechanical trauma. The authors studied a sample of 107 patients with vocal nodules, looking for a possible correlation with microwebs due to the predicted involvement in the vibration of vocal cord margins. Glottic proportion, type of glottic closure, nodule location and the main complaints in patients with microwebs were compared with those in a sample of patients without microwebs. In the present study, microwebs were found in 9.4% of the patients, who showed much smaller glottic proportion than patients with micronodules only. Furthermore, vocal nodule location was not related to the presence and/or absence of laryngeal microwebs.
喉微蹼的病因和发病机制是异质性的，在大多数情况下它们是偶然发现的。也有人提出微蹼可能是一种家族性特征，代表一种胚后发育的胚胎残留结构，可能会改变声带的生物力学和振动特性。声带小结是沿声带边缘的小良性肿物，好发于前1/3与中1/3交界处，通常由机械性创伤引起。作者研究了107例声带小结患者的样本，由于预计微蹼会累及声带边缘的振动，因此寻找其与微蹼之间可能存在的相关性。将有微蹼患者的声门比例、声门闭合类型、小结位置及主要症状与无微蹼患者样本进行比较。在本研究中，9.4%的患者发现有微蹼，这些患者的声门比例比仅患有微小结节的患者小得多。此外，声带小结的位置与喉微蹼的存在与否无关。
