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[术前同步放化疗(CCRT)诱导治疗期间行肺上沟瘤根治性切除术——1例报告]

[Complete resection of Pancoast tumor while receiving preoperative concurrent chemoradiotherapy (CCRT) as an induction therapy--report of a case].

作者信息

Matsuoka Takahisa, Sugi Kazuro, Matsuda Eisuke, Umemori Yoshiki, Okabe Kazunori, Hirazawa Katsutoshi, Azuma Toshitaka

机构信息

Dept. of Chest Surgery, National Hospital Organization, National Sanyo Hospital.

出版信息

Gan To Kagaku Ryoho. 2006 Nov;33(11):1625-8.

Abstract

A 60-year-old man complaining of right shoulder pain and numbness of right arm was diagnosed with Pancoast tumor (invasive right apical lung cancer). Chest CT scan showed a tumor, 5 cm in diameter, in the right apex invading the right posterior chest wall. The patient received preoperative CCRT (RT: 40 Gy/20 Fr, cisplatin: CDDP and etoposide: ETP), resulting in tumor regression (PR). The patient underwent right upper lobectomy (ND 2a), partial resection of the 1st-3rd ribs and Th 1 nerve. Pathological examination demonstrated no live cancer cells and organization of necrotic tissue in the lung and intercostal region (Ef. 3). The patient received postoperative chemotherapy (CDDP+ETP) and was discharged. He did well without any tumor recurrence for 1 year postoperatively. CCRT seems effective and is one of the standard treatments for Pancoast tumor.

摘要

一名60岁男性,因右肩疼痛和右臂麻木就诊,被诊断为潘科斯特瘤(右肺尖浸润性癌)。胸部CT扫描显示右肺尖有一个直径5厘米的肿瘤,侵犯右后胸壁。患者接受了术前同步放化疗(放疗:40 Gy/20次,顺铂:CDDP和依托泊苷:ETP),肿瘤缩小(PR)。患者接受了右上叶切除术(ND 2a)、第1 - 3肋骨部分切除术和胸1神经切除术。病理检查显示肺和肋间区域无存活癌细胞,坏死组织机化(Ef. 3)。患者接受了术后化疗(CDDP + ETP)后出院。术后1年患者情况良好,无肿瘤复发。同步放化疗似乎有效,是潘科斯特瘤的标准治疗方法之一。

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