Urabe N, Shiba M, Odaka E, Suzuki M, Fujisawa T, Yamaguchi Y
Dept. of Surgery, School of Medicine, Chiba University.
Gan To Kagaku Ryoho. 1990 Oct;17(10):2091-5.
A case of 51-year-old woman, she was suffered from primary parotic cancer and the right parotic gland was resected in 1980, and pulmonary metastatic nodule was also operated in 1982. She was admitted in our institute with complaint of bloody sputum and cough in 1989, and diagnosed as pulmonary and splenic metastasis of parotic cancer. Two courses of combined chemotherapy, with CDDP by administration through bronchial artery, with CDDP and VDS by a systematic intravenous injection, was done. With these therapies, partial responses were obtained in the metastatic lesions, so spleen and left lower lobe of lung were resected. In the histological examination of the resected tumors, tumor cells were nearly disappeared, and we obtained Ef-2 effect according to the general rule for clinical and pathological record of lung cancer. She was discharged after one more chemotherapy and with no sign of recurrence now. We reported this case because of the possibility of the effective adjuvant therapy of the case with multiple lesions of cancer metastasis, and the rare case of splenic metastasis.
一名51岁女性患者，1980年因原发性腮腺癌接受右侧腮腺切除术，1982年又对肺部转移结节进行了手术。1989年，她因咯血和咳嗽入住我院，被诊断为腮腺癌肺脾转移。进行了两个疗程的联合化疗，一个疗程是通过支气管动脉给予顺铂，另一个疗程是通过全身静脉注射给予顺铂和长春地辛。通过这些治疗，转移病灶获得了部分缓解，因此切除了脾脏和左肺下叶。在切除肿瘤的组织学检查中，肿瘤细胞几乎消失，根据肺癌临床和病理记录的一般规则，我们获得了Ef-2效应。在再进行一次化疗后她出院了，目前没有复发迹象。我们报告这个病例是因为该病例有进行癌症转移多病灶有效辅助治疗的可能性，以及脾脏转移这种罕见情况。
