Mocellin Ramon, Lubman Dan I, Lloyd John, Tomlinson E Bruce, Velakoulis Dennis
Neuropsychiatry Unit, Melbourne Neuropsychiatry Center, Royal Melbourne Hospital, Melbourne, Austrailia.
Psychiatry Clin Neurosci. 2006 Dec;60(6):761-3. doi: 10.1111/j.1440-1819.2006.01593.x.
A case of presumed Hashimoto's encephalopathy (HE) is presented. The presentation included memory loss, delusions, functional decline and culminated in a generalized seizure. Anti-thyroid antibodies were detected and symptoms resolved with prednisolone. Patients with HE may present with prominent neuropsychiatric symptoms, attract psychiatric diagnoses and present to psychiatric services. Primarily a diagnosis of exclusion, HE should be considered in cases of encephalopathy in which standard investigations are negative.
本文报告一例疑似桥本脑病(HE)的病例。临床表现包括记忆力减退、妄想、功能衰退,最终发展为全身性癫痫发作。检测到抗甲状腺抗体,使用泼尼松龙后症状缓解。HE患者可能出现明显的神经精神症状,容易被诊断为精神疾病并转诊至精神科。HE主要是一种排除性诊断,在标准检查结果为阴性的脑病病例中应考虑该病。