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了解副肿瘤性和遗传性小脑共济失调的病理生理学。

Understanding the physiopathology of paraneoplastic and genetic cerebellar ataxia.

作者信息

Honnorat J

出版信息

J Neurol Neurosurg Psychiatry. 2006 Dec;77(12):1299-300. doi: 10.1136/jnnp.2006.100594.

DOI:10.1136/jnnp.2006.100594
PMID:17110741
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2077414/
Abstract

Antibodies as diagnostic markers of ataxia

摘要

抗体作为共济失调的诊断标志物

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Understanding the physiopathology of paraneoplastic and genetic cerebellar ataxia.了解副肿瘤性和遗传性小脑共济失调的病理生理学。
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本文引用的文献

1
Protein kinase Cgamma autoimmunity in paraneoplastic cerebellar degeneration and non-small-cell lung cancer.副肿瘤性小脑变性和非小细胞肺癌中的蛋白激酶Cγ自身免疫
J Neurol Neurosurg Psychiatry. 2006 Dec;77(12):1359-62. doi: 10.1136/jnnp.2006.097188. Epub 2006 Jun 26.
2
Advances in paraneoplastic neurological syndromes.副肿瘤性神经系统综合征的进展
Curr Opin Oncol. 2004 Nov;16(6):614-20. doi: 10.1097/01.cco.0000142486.89472.eb.
3
FDG-PET improves tumour detection in patients with paraneoplastic neurological syndromes.氟代脱氧葡萄糖正电子发射断层扫描(FDG-PET)可提高副肿瘤性神经综合征患者的肿瘤检测率。
Brain. 2004 Oct;127(Pt 10):2331-8. doi: 10.1093/brain/awh247. Epub 2004 Sep 10.
4
Recommended diagnostic criteria for paraneoplastic neurological syndromes.副肿瘤性神经系统综合征的推荐诊断标准。
J Neurol Neurosurg Psychiatry. 2004 Aug;75(8):1135-40. doi: 10.1136/jnnp.2003.034447.
5
Missense mutations in the regulatory domain of PKC gamma: a new mechanism for dominant nonepisodic cerebellar ataxia.蛋白激酶Cγ调节域中的错义突变:显性非发作性小脑共济失调的新机制。
Am J Hum Genet. 2003 Apr;72(4):839-49. doi: 10.1086/373883. Epub 2003 Mar 17.
6
Altered trafficking of membrane proteins in purkinje cells of SCA1 transgenic mice.SCA1转基因小鼠浦肯野细胞中膜蛋白转运的改变。
Am J Pathol. 2001 Sep;159(3):905-13. doi: 10.1016/S0002-9440(10)61766-X.
7
The polyglutamine expansion in spinocerebellar ataxia type 6 causes a beta subunit-specific enhanced activation of P/Q-type calcium channels in Xenopus oocytes.脊髓小脑共济失调6型中的多聚谷氨酰胺扩展导致非洲爪蟾卵母细胞中P/Q型钙通道的β亚基特异性激活增强。
J Neurosci. 2000 Sep 1;20(17):6394-403. doi: 10.1523/JNEUROSCI.20-17-06394.2000.
8
Small-cell lung cancer, paraneoplastic cerebellar degeneration and the Lambert-Eaton myasthenic syndrome.小细胞肺癌、副肿瘤性小脑变性和兰伯特-伊顿肌无力综合征。
Brain. 1997 Aug;120 ( Pt 8):1279-300. doi: 10.1093/brain/120.8.1279.
9
Incidence of serum anti-P/O-type and anti-N-type calcium channel autoantibodies in the Lambert-Eaton myasthenic syndrome.兰伯特-伊顿肌无力综合征患者血清抗P/O型和抗N型钙通道自身抗体的发生率。
J Neurol Sci. 1997 Mar 20;147(1):35-42. doi: 10.1016/s0022-510x(96)05303-8.
10
Paraneoplastic cerebellar degeneration. III. Cerebellar degeneration, cancer, and the Lambert-Eaton myasthenic syndrome.副肿瘤性小脑变性。III. 小脑变性、癌症与兰伯特-伊顿肌无力综合征。
Neurology. 1992 Oct;42(10):1944-50. doi: 10.1212/wnl.42.10.1944.