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Natural dibenzoxazepinones from leaves of Carex distachya: Structural elucidation and radical scavenging activity.

作者信息

Fiorentino Antonio, D'Abrosca Brigida, Pacifico Severina, Cefarelli Giuseppe, Uzzo Piera, Monaco Pietro

机构信息

Dipartimento di Scienze della Vita, Seconda Università degli studi di Napoli, via Vivaldi 43, 81100 Caserta, Italy.

出版信息

Bioorg Med Chem Lett. 2007 Feb 1;17(3):636-9. doi: 10.1016/j.bmcl.2006.11.002. Epub 2006 Nov 6.

DOI:10.1016/j.bmcl.2006.11.002
PMID:17112723
Abstract

Two new dibenzoxazepinones have been isolated from the leaves of Carex distachya, an herbaceous plant growing in the Mediterranean area. The structures have been elucidated on the basis of their spectroscopic properties. Bidimensional NMR (DQ-COSY, TOCSY, NOESY, ROESY, HSQC, and HMBC) furnished important data useful for the characterization of the molecules. The compounds have been assayed, for the antioxidant activity, by measuring its capacity to scavenge the DPPH, the superoxide anion, and nitric oxide radicals.

摘要

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