Raguin L Guy, Ciobanu Luisa
Department of Mechanical Engineering, University of Illinois at Urbana-Champaign, IL, USA.
J Magn Reson. 2007 Feb;184(2):337-43. doi: 10.1016/j.jmr.2006.10.015. Epub 2006 Nov 16.
The understanding of fluid transport in miniaturized flow devices is an important component in the design of flow cells, micromixers, and microreactors. In this manuscript, we employ NMR in the form of a voxel-selective multiple modulation multiple echo sequence (MMMEV) to monitor average velocities in individual microchannels inside a six-channel network. The technique produces average velocities which are consistent with the imposed flow rates. In addition, we take advantage of the short acquisition time (32 ms per velocity component) of the technique to quantitatively track the time evolution of the fluid velocity in a pulsatile flow phantom.
理解小型流动装置中的流体传输是流动池、微混合器和微反应器设计中的一个重要组成部分。在本论文中,我们采用体素选择性多重调制多重回波序列(MMMEV)形式的核磁共振(NMR)来监测六通道网络内各个微通道中的平均流速。该技术产生的平均流速与施加的流速一致。此外,我们利用该技术较短的采集时间(每个速度分量32毫秒)来定量跟踪脉动流模型中流体速度的时间演变。