Iwasa K, Sandvik A K, Waldum H L
Department of Medicine, University Hospital, Trondheim, Norway.
Agents Actions Suppl. 1991;33:429-34. doi: 10.1007/978-3-0348-7309-3_34.
This study was performed to examine the effect of cAMP levels on histamine release in the isolated rat stomach. Pentagastrin-induced histamine release was unaffected by phosphodiesterase inhibition, and pentagastrin itself had no phosphodiesterase-like effect. The results support previous observations showing that histamine is likely to be the mediator of the acid secretagogue effect of (penta) gastrin.