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犬弓首蛔虫所致肝内脏幼虫移行症:CT及超声检查结果

Hepatic visceral larva migrans of Toxocara canis: CT and sonographic findings.

作者信息

Chang Samuel, Lim Jae Hoon, Choi Dongil, Park Cheol Keun, Kwon Nam-Hee, Cho Seung-Yull, Choi Dong-Chull

机构信息

Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, Seoul, South Korea 135-230.

出版信息

AJR Am J Roentgenol. 2006 Dec;187(6):W622-9. doi: 10.2214/AJR.05.1416.

DOI:10.2214/AJR.05.1416
PMID:17114516
Abstract

OBJECTIVE

The aim of this study was to describe the CT and sonographic findings of hepatic visceral larva migrans of Toxocara canis.

MATERIALS AND METHODS

Fifty-four patients (44 men, 10 women; age range, 30-80 years; mean age, 53 years) with serologically confirmed visceral larva migrans of Toxocara canis underwent evaluation of the liver with CT (n = 25), sonography (n = 48), or both. Two radiologists used consensus for retrospective evaluation of CT and sonographic findings. Correlation between the presence and severity of hepatic abnormalities on images and the degree of peripheral eosinophilia was assessed.

RESULTS

Seventeen (68%) of 25 patients who underwent CT had single or multiple ill-defined, oval or elongated, small, low-attenuating lesions in the liver. Eighteen (38%) of 48 patients who underwent sonography had single or multiple small, poorly defined, oval or elongated, hypoechoic scattered focal lesions in the liver. In the 19 patients who underwent both CT and sonography, the two techniques had no significant difference in rate of detection of hepatic lesions (p = 0.375, McNemar test). The lesion numbers on CT and sonography showed excellent linear correlation (r = 0.844, p = 0.001) by Pearson's correlation test. An independent samples t test showed that eosinophil count and percentage in the peripheral blood were significantly higher in patients with hepatic lesions on CT and sonography than in patients without lesions.

CONCLUSION

CT and sonographic findings of hepatic visceral larva migrans of T. canis are multiple, ill-defined, oval or elongated, small, nodular lesions scattered in the liver parenchyma. The presence of hepatic lesions on images was associated with higher peripheral eosinophil count and percentage.

摘要

目的

本研究旨在描述犬弓首蛔虫肝内幼虫移行症的CT及超声表现。

材料与方法

54例经血清学确诊为犬弓首蛔虫内脏幼虫移行症的患者(44例男性,10例女性;年龄范围30 - 80岁,平均年龄53岁)接受了肝脏CT检查(n = 25)、超声检查(n = 48)或两者均做。两名放射科医生采用一致意见对CT及超声检查结果进行回顾性评估。评估图像上肝脏异常的存在及严重程度与外周血嗜酸性粒细胞增多程度之间的相关性。

结果

25例行CT检查的患者中,17例(68%)肝脏出现单个或多个边界不清、椭圆形或细长形、小的低密度病灶。48例行超声检查的患者中,18例(38%)肝脏出现单个或多个边界不清、椭圆形或细长形、低回声的散在局灶性病灶。在19例同时接受CT和超声检查的患者中,两种检查技术对肝脏病灶的检出率无显著差异(p = 0.375,McNemar检验)。通过Pearson相关性检验,CT和超声检查的病灶数量显示出极好的线性相关性(r = 0.844,p = 0.001)。独立样本t检验显示,CT和超声检查发现肝脏有病灶的患者外周血嗜酸性粒细胞计数及百分比显著高于无病灶的患者。

结论

犬弓首蛔虫肝内幼虫移行症的CT及超声表现为多个边界不清、椭圆形或细长形、小的结节状病灶散在于肝实质内。图像上肝脏病灶的存在与外周血嗜酸性粒细胞计数及百分比升高有关。

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