弓蛔虫所致肝脓肿的临床特征及病情进展
Clinical characteristics and progression of liver abscess caused by toxocara.
作者信息
Ha Kyung Ho, Song Jung Eun, Kim Byung Seok, Lee Chang Hyeong
机构信息
Kyung Ho Ha, Department of Internal Medicine, Daegu Medical Center, Daegu 41845, South Korea.
出版信息
World J Hepatol. 2016 Jun 28;8(18):757-61. doi: 10.4254/wjh.v8.i18.757.
AIM
To evaluate the clinical characteristics and progression of liver abscess caused by toxocara.
METHODS
We retrospectively reviewed the medical records of patients with serum IgG antibody to Toxocara canis and liver abscess diagnosed using abdominal computed tomography between February 2010 and February 2015. Among 84 patients exhibiting serum IgG antibody to Toxocara canis, 34 patients were diagnosed with liver asbscess and treated with albendazole. A follow-up period of 1 year was conducted.
RESULTS
Mean patient age was 53 (34-79) years, with 26 (76.5%) patients being male. Twenty-one (61.7%) patients were moderate or heavy drinkers, 23 (67.6%) patients had a history of eating raw meat or liver and 6 (17.6%) patients owned pet dogs or cats. Main patient symptoms consisted of right upper quadrant pain, fever, and fatigue; 18 (52.9%) patients, however, presented with no symptoms. Lung involvement was detected in 444 (11.7%) patients. The eosinophil count increased in 29 (85.3%) patients at initial diagnosis, and decreased in most patients after albendazole treatment. The initial serum IgE level increased in 25 (73.5%) patients, but exhibited various response levels after albendazole treatment. Liver abscess formation improved in all patients.
CONCLUSION
The liver abscess was improved with albendazole treatment.
目的
评估弓蛔虫所致肝脓肿的临床特征及病情进展。
方法
我们回顾性分析了2010年2月至2015年2月期间，经腹部计算机断层扫描诊断为犬弓蛔虫血清IgG抗体阳性及肝脓肿患者的病历。在84例犬弓蛔虫血清IgG抗体阳性患者中，34例被诊断为肝脓肿并接受阿苯达唑治疗。进行了为期1年的随访。
结果
患者平均年龄为53岁（34 - 79岁），男性26例（76.5%）。21例（61.7%）患者为中度或重度饮酒者，23例（67.6%）患者有生食肉类或肝脏的病史，6例（17.6%）患者养有宠物狗或猫。主要症状包括右上腹疼痛、发热和乏力；然而，18例（52.9%）患者无症状。44例（11.7%）患者检测到肺部受累。29例（85.3%）患者初诊时嗜酸性粒细胞计数升高，阿苯达唑治疗后大多数患者计数下降。25例（73.5%）患者初始血清IgE水平升高，但阿苯达唑治疗后呈现不同的反应水平。所有患者肝脓肿形成均有改善。
结论
阿苯达唑治疗使肝脓肿病情改善。
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