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烧伤损伤与康复营养管理实用指南。

Practical guidelines for nutritional management of burn injury and recovery.

作者信息

Prelack Kathy, Dylewski Maggie, Sheridan Robert L

机构信息

Department of Clinical Nutrition, Shriners Hospital for Children, Boston, MA 02114, USA.

出版信息

Burns. 2007 Feb;33(1):14-24. doi: 10.1016/j.burns.2006.06.014. Epub 2006 Nov 20.

Abstract

Nutrition practice in burn injury requires a multifaceted approach aimed at providing metabolic support during a heightened inflammatory state, while accommodating surgical and medical needs of the patient. Nutritional assessment and determination of nutrient requirements is challenging, particularly given the metabolic disarray that frequently accompanies inflammation. Nutritional therapy requires careful decision making, regarding the safe use of enteral or parenteral nutrition and the aggressiveness of nutrient delivery given the severity of the patient's illness and response to treatment. With the discovery that specific nutrients can actually alter the course of disease, the role of nutrition support in critical illness has shifted from one of preventing malnutrition to one of disease modulation. Today the use of glutamine, arginine, essential fatty acids, and other nutritional factors for their effects on immunity and cell regulation is becoming more common, although the evidence is often lagging. An exciting dichotomy exits, forcing nutrition support specialists to make responsible choices while remaining open to new potential helpful therapeutic options.

摘要

烧伤患者的营养治疗需要采取多方面的方法,旨在为处于高度炎症状态的患者提供代谢支持,同时满足患者的手术和医疗需求。营养评估和确定营养需求具有挑战性,特别是考虑到炎症经常伴随的代谢紊乱。营养治疗需要谨慎决策,鉴于患者病情的严重程度和对治疗的反应,安全使用肠内或肠外营养以及营养输送的积极程度。随着发现特定营养素实际上可以改变疾病进程,营养支持在危重病中的作用已从预防营养不良转变为疾病调节。如今,使用谷氨酰胺、精氨酸、必需脂肪酸和其他营养因素来影响免疫和细胞调节变得越来越普遍,尽管证据往往滞后。一个令人兴奋的二分法出现了,迫使营养支持专家做出负责任的选择,同时对新的潜在有益治疗选择保持开放态度。

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