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接受腹腔镜转换为Roux-en-Y胃旁路术的病态肥胖患者抗反流手术后的解剖学发现及结果

Anatomic findings and outcomes after antireflux procedures in morbidly obese patients undergoing laparoscopic conversion to Roux-en-Y gastric bypass.

作者信息

Kellogg Todd A, Andrade Raphael, Maddaus Michael, Slusarek Bridget, Buchwald Henry, Ikramuddin Sayeed

机构信息

Division of Bariatric Surgery, Department of Surgery, University of Minnesota School of Medicine, Minnesota, Michigan, USA.

出版信息

Surg Obes Relat Dis. 2007 Jan-Feb;3(1):52-7; discussion 58-9. doi: 10.1016/j.soard.2006.08.011. Epub 2006 Nov 20.

Abstract

BACKGROUND

To report the anatomic findings and outcomes in patients undergoing laparoscopic takedown of Nissen fundoplication with conversion to Roux-en-Y gastric bypass.

METHODS

We reviewed the records of patients who underwent laparoscopic Nissen takedown with conversion to Roux-en-Y gastric bypass from January 2001 to April 2006 at the University of Minnesota Medical Center.

RESULTS

Eleven patients were identified. Nine patients had gastroesophageal reflux disease preoperatively, of whom six underwent 24-hour pH monitoring. In 2 patients, the pH study findings were negative. Eight prior procedures had been performed laparoscopically. Eight patients were women. The mean age was 44 years. The average body mass index preoperatively was 44 kg/m(2) (range 35-61). The mean follow-up was 13.8 months (range 4-39). The body mass index at follow-up was 30.2 kg/m(2). The operative time was 349 minutes (range 222-624). The hospital length of stay was 3.4 days (range 2-6). No conversions to open surgery were required. No major short-term complications developed. Minor complications included wound or drain site infection in 3 patients, with abscess in 2, pressure sore of the lateral aspect of the foot in 1, pneumonia in 2, and marginal ulcer in 2 patients. No strictures were observed. One internal hernia occurred. Of the 9 patients with gastroesophageal reflux disease preoperatively, all had 100% improvement in symptoms, with complete resolution in 7 (78%). Wrap disruption was present in 5 (45%) of 11 patients. Herniation of an intact wrap had occurred in 1 patient. One patient had both herniation and wrap disruption.

CONCLUSION

Laparoscopic conversion of Nissen fundoplication to Roux-en-Y gastric bypass is a feasible salvage operation for recurrent gastroesophageal reflux disease in the morbidly obese. The incidence of wrap disruption appears to be relatively high and the incidence of intact wrap herniation low in obese patients after failed Nissen fundoplication, suggesting that the mechanism of failure after primary antireflux surgery in obese patients may be different than that in normal-weight patients.

摘要

背景

报告接受腹腔镜下尼森胃底折叠术转为Roux-en-Y胃旁路术患者的解剖学发现及手术结果。

方法

我们回顾了2001年1月至2006年4月在明尼苏达大学医学中心接受腹腔镜下尼森胃底折叠术并转为Roux-en-Y胃旁路术患者的病历。

结果

共确定11例患者。9例患者术前患有胃食管反流病,其中6例接受了24小时pH监测。2例患者pH研究结果为阴性。8例之前的手术为腹腔镜手术。8例患者为女性。平均年龄44岁。术前平均体重指数为44kg/m²(范围35 - 61)。平均随访时间为13.8个月(范围4 - 39个月)。随访时体重指数为30.2kg/m²。手术时间为349分钟(范围222 - 624分钟)。住院时间为3.4天(范围2 - 6天)。无需转为开放手术。未出现重大短期并发症。轻微并发症包括3例患者伤口或引流部位感染,2例患者出现脓肿,1例患者足部外侧压疮,2例患者肺炎,2例患者边缘溃疡。未观察到狭窄。发生1例内疝。术前患有胃食管反流病的9例患者中,所有患者症状均有100%改善,7例(78%)完全缓解。11例患者中有5例(45%)出现胃底折叠术包绕结构破裂。1例患者出现完整包绕结构疝出。1例患者同时出现疝出和包绕结构破裂。

结论

对于病态肥胖患者复发性胃食管反流病,腹腔镜下将尼森胃底折叠术转为Roux-en-Y胃旁路术是一种可行的挽救手术。在尼森胃底折叠术失败后的肥胖患者中,包绕结构破裂的发生率似乎相对较高,而完整包绕结构疝出的发生率较低,这表明肥胖患者初次抗反流手术后失败的机制可能与正常体重患者不同。

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