胃底折叠术后失败:再次行胃底折叠术?是否有胃切除术的空间?在哪些临床情况下适用?
FAILURE AFTER FUNDOPLICATION: RE-FUNDOPLICATION? IS THERE A ROOM FOR GASTRECTOMY? IN WHICH CLINICAL SCENARIES?
作者信息
Braghetto Italo, Csendes Attila
机构信息
Department of Surgery, Hospital Clínico "Dr. José J. Aguirre", Faculty of Medicine, University of Chile, Santiago Chile.
出版信息
Arq Bras Cir Dig. 2019 Aug 26;32(2):e1440. doi: 10.1590/0102-672020190001e1440.
BACKGROUND
Re-fundoplication is the most often procedure performed after failed fundoplication, but re-failure is even higher.
AIM
The objectives are: a) to discuss the results of fundoplication and re-fundoplication in these cases, and b) to analyze in which clinical situation there is a room for gastrectomy after failed fundoplication.
METHOD
This experience includes 104 patients submitted to re-fundoplication after failure of the initial operation, 50 cases of long segment Barrett´s esophagus and 60 patients with morbid obesity, comparing the postoperative outcome in terms of clinical, endoscopic, manometric and 24h pH monitoring results.
RESULTS
In patients with failure after initial fundoplication, redo-fundoplication shows the worst clinical results (symptoms, endoscopic esophagitis, manometry and 24 h pH monitoring). In patients with long segment Barrett´s esophagus, better results were observed after fundoplication plus Roux-en-Y distal gastrectomy and in obese patients similar results regarding symptoms, endoscopic esophagitis and 24h pH monitoring were observed after both fundoplication plus distal gastrectomy or laparoscopic resectional gastric bypass, while regarding manometry, normal LES pressure was observed only after fundoplication plus distal gastrectomy.
CONCLUSION
Distal gastrectomy is recommended for patients with failure after initial fundoplication, patients with long segment Barrett´s esophagus and obese patients with gastroesophageal reflux disease and Barrett´s esophagus. Despite its higher morbidity, this procedure represents an important addition to the surgical armamentarium.
背景
再次行胃底折叠术是初次胃底折叠术失败后最常实施的手术,但再次失败率甚至更高。
目的
目标如下:a)讨论这些病例中行胃底折叠术及再次胃底折叠术的结果,b)分析初次胃底折叠术失败后在何种临床情况下有行胃切除术的空间。
方法
本经验纳入了104例初次手术失败后接受再次胃底折叠术的患者、50例长节段巴雷特食管患者和60例病态肥胖患者,比较临床、内镜、测压及24小时pH监测结果方面的术后结局。
结果
初次胃底折叠术失败的患者中,再次胃底折叠术显示出最差的临床结果(症状、内镜下食管炎、测压及24小时pH监测)。在长节段巴雷特食管患者中,胃底折叠术加Roux-en-Y远端胃切除术后观察到更好的结果;在肥胖患者中,胃底折叠术加远端胃切除术或腹腔镜切除性胃旁路术后在症状、内镜下食管炎及24小时pH监测方面观察到相似结果,而在测压方面,仅胃底折叠术加远端胃切除术后观察到LES压力正常。
结论
对于初次胃底折叠术失败的患者、长节段巴雷特食管患者以及患有胃食管反流病和巴雷特食管的肥胖患者,建议行远端胃切除术。尽管其发病率较高,但该手术是手术治疗手段的一项重要补充。