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腹腔镜胃旁路手术治疗病态肥胖患者胃食管反流病的抗反流手术后:初步经验

Laparoscopic gastric bypass after antireflux surgery for the treatment of gastroesophageal reflux in morbidly obese patients: initial experience.

作者信息

Raftopoulos Ioannis, Awais Omar, Courcoulas Anita P, Luketich James D

机构信息

Department of Surgery, Division of Thoracic and Foregut Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA.

出版信息

Obes Surg. 2004 Nov-Dec;14(10):1373-80. doi: 10.1381/0960892042583950.

Abstract

BACKGROUND

Laparoscopic Roux-en-Y gastric bypass (LRYGBP) has been proven effective against gastroesophageal reflux disease (GERD) in morbidly obese patients. We present our experience with revision of antireflux procedures to LRYGBP in obese patients with recurrent GERD, weight gain or a combination of both and discuss the indications and technical considerations involved.

METHODS

Between June 2000 and December 2003, 7 morbidly obese patients with a mean BMI of 37.5 kg/m(2) underwent revision of an antireflux procedure to LRYGBP by our group. Important steps of the revision include dissection of the diaphragmatic crura and gastroesophageal fat pad, reduction and repair of hiatal hernia, and complete take-down of the wrap to avoid stapling over the fundoplication which can create an obstructed, septated pouch.

RESULTS

Mean operative time was 6 hr 12 min and length of stay was 4.8 days. There were 3 major complications postoperatively and no deaths. During follow-up, 5 patients developed anastomotic strictures and 2 patients were re-explored for gastric remnant herniation and intestinal obstruction. At a mean follow-up of 24 (3-44) months, mean excess weight loss was 70.7% and 14/20 (70%) co-morbid conditions were improved or resolved. GERD evaluation with the GERD-HRQL scale showed a significant reduction of GERD scores postoperatively (P =0.006).

CONCLUSIONS

Although LRYGBP after antireflux surgery is a technically more difficult procedure with a higher morbidity, it is feasible and effective for the treatment of recurrent GERD and worsening obesity with the additional advantage of weight loss and improvement of co-morbidities.

摘要

背景

腹腔镜Roux-en-Y胃旁路术(LRYGBP)已被证明对病态肥胖患者的胃食管反流病(GERD)有效。我们介绍了在复发性GERD、体重增加或两者兼有的肥胖患者中,将抗反流手术改为LRYGBP的经验,并讨论了相关的适应症和技术要点。

方法

2000年6月至2003年12月,我们团队对7例平均BMI为37.5kg/m²的病态肥胖患者进行了抗反流手术改为LRYGBP的手术。手术的重要步骤包括膈肌脚和胃食管脂肪垫的分离、食管裂孔疝的复位和修复,以及完全拆除胃底折叠术以避免在胃底折叠术上进行吻合,这可能会形成梗阻性、分隔性胃囊。

结果

平均手术时间为6小时12分钟,住院时间为4.8天。术后有3例主要并发症,无死亡病例。随访期间,5例患者出现吻合口狭窄,2例患者因胃残余疝和肠梗阻再次接受手术。平均随访24(3 - 44)个月时,平均超重减轻率为70.7%,20种合并症中的14种(70%)得到改善或缓解。用GERD-HRQL量表进行的GERD评估显示术后GERD评分显著降低(P = 0.006)。

结论

尽管抗反流手术后的LRYGBP在技术上更具难度且发病率更高,但对于治疗复发性GERD和日益严重的肥胖症是可行且有效的,还具有减重和改善合并症的额外优势。

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