Abou-Elela A, Reyad I, Morsy A, Elgammal M, Bedair A S, Abdelkader M
Urology Department, Cairo University, 1, Obour Buildings, Salah Salem Street, Nasr City, Cairo 35290, Egypt.
Eur J Surg Oncol. 2007 Feb;33(1):96-101. doi: 10.1016/j.ejso.2006.10.006. Epub 2006 Nov 21.
Bladder neck preservation during radical prostatectomy has been advocated for improving urinary continence. We evaluate bladder neck preservation looking at continence rates, surgical cancer control and bladder neck contracture.
A total of 40 patients underwent retropubic radical prostatectomy for clinically localized carcinoma of the prostate. The prostatic urethra was dissected in continuity with the bladder away from the lumen of the prostate, which allows for a true urethra-to-urethra anastomosis.
Continence was noted immediately in 26 patients, within 2 weeks in 9 and within 6 weeks in 3. Only 2 patients required pads 3 months postoperatively. Microscopic positive surgical margins were noted in 2 of 40 patients. In 1 patient the urethral margins were not involved with carcinoma. In the other patient the urethra was not the sole positive margin and microscopic positive margins were noted elsewhere. Early results of cancer control were good.
Early follow-up of this technique of radical retropubic prostatectomy suggest that preservation of the continence mechanism at the level of the bladder neck and prostatic urethra results in significantly improved postoperative urinary continence without adversely affecting cancer control.
根治性前列腺切除术中保留膀胱颈已被提倡用于改善尿失禁。我们通过观察尿失禁发生率、手术癌症控制情况和膀胱颈挛缩来评估膀胱颈保留情况。
共有40例患者因临床局限性前列腺癌接受耻骨后根治性前列腺切除术。前列腺尿道与膀胱连续分离,远离前列腺管腔,这使得真正的尿道对尿道吻合成为可能。
26例患者术后立即实现控尿,9例在2周内实现控尿,3例在6周内实现控尿。只有2例患者术后3个月需要使用尿垫。40例患者中有2例出现显微镜下手术切缘阳性。1例患者尿道切缘未被癌累及。另1例患者尿道不是唯一的阳性切缘,其他部位发现显微镜下阳性切缘。癌症控制的早期结果良好。
对这种耻骨后根治性前列腺切除术技术的早期随访表明,在膀胱颈和前列腺尿道水平保留控尿机制可显著改善术后尿失禁,且不会对癌症控制产生不利影响。