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一条北非锯鳞蝰(爬行纲:蛇目)对人类进行有毒咬伤后的临床、生理及血清学观察

Clinical, physiological and serological observations of a human following a venomous bite by Macrovipera lebetina lebetina (Reptilia: Serpentes).

作者信息

Göçmen Bayram, Arikan Huseyin, Ozbel Yusuf, Mermer Ahmet, Ciçek Kerim

机构信息

Ege University Science Faculty, Department of Zoology, Izmir, Turkey.

出版信息

Turkiye Parazitol Derg. 2006;30(2):158-62.

Abstract

A researcher, a 40 year-old male, was bitten on his finger accidentally by a 75 cm long, adult male blunt-nosed viper, Macrovipera lebetina lebetina (Linnaeus) that had been collected from northern Cyprus during laboratory work in the Zoology Section, Biology Department of the Ege University Faculty of Science. The clinical signs, physiological and biochemical changes soon after the venomous bite by the blunt-nosed viper as well as the electrophoretic separation of plasma proteins of the patient have been presented here. Serious important symptoms (edema, hypotension shock, hemorrhage, tissue necrosis, and melanoderma) developed and major quantitative differences in the fractions of albumin, globulin and albumin/globulin ratios were detected. On the other hand, the measurements carried out in blood smears and biochemical results indicated the decrease in RBC, MCV, MHV and a decrease in the diameter of red blood cells, as well as an increase in WBC.

摘要

一名40岁男性研究人员在伊兹密尔大学理学院生物系动物学教研室进行实验室工作时,手指意外被一条从塞浦路斯北部采集的75厘米长成年雄性钝鼻蝰蛇(Macrovipera lebetina lebetina,林奈)咬伤。本文呈现了被钝鼻蝰蛇咬伤后不久的临床症状、生理和生化变化,以及患者血浆蛋白的电泳分离情况。出现了严重的重要症状(水肿、低血压休克、出血、组织坏死和黑皮病),并检测到白蛋白、球蛋白组分及白蛋白/球蛋白比值存在重大定量差异。另一方面,血液涂片检查和生化结果显示红细胞、平均红细胞体积、平均血红蛋白量减少,红细胞直径减小,白细胞增多。

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