Chippaux J P
Travail de l'IRD, La Paz, Bolivie.
Med Trop (Mars). 2006 Oct;66(5):423-8.
Vipers are the main cause of the snake envenomations on all continents except Australia where they are none. Viper envenomation may lead to a minimal inflammatory syndrome with clinical (pain, edema) and biological (hyperleukocytosis, proteinuria) manifestations that may be accompanied by hypotension or shock. Emergency situations are due to hemorrhagic syndrome. In frequent cases in which envenomation is limited to a dramatic decrease in coagulation factors without clinical manifestations, severe local or systemic hemorrhage may occur especially if treatment is delayed. Necrotic complications around the bite or in distant vital organs are not uncommon and require careful medical and surgical surveillance. Intravenous antivenom therapy is the only effective treatment. It should be given as soon as possible but can be effective even when administered several days after the bite.
除了澳大利亚(当地没有蝰蛇)之外,在其他各大洲,蝰蛇都是蛇咬伤中毒的主要原因。蝰蛇咬伤中毒可能导致轻微的炎症综合征,伴有临床症状(疼痛、水肿)和生物学表现(白细胞增多、蛋白尿),还可能伴有低血压或休克。紧急情况是由出血综合征引起的。在常见的情况下,中毒仅表现为凝血因子急剧下降而无临床表现,但如果治疗延迟,可能会发生严重的局部或全身出血。咬伤部位周围或远处重要器官出现坏死并发症并不罕见,需要仔细的医学和外科监测。静脉注射抗蛇毒血清疗法是唯一有效的治疗方法。应尽快给药,但即使在咬伤几天后给药也可能有效。