Simionescu Olga, Costache Mariana, Testori Alessandro
The 1st Department of Dermatology, Colentina Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
J Cell Mol Med. 2006 Oct-Dec;10(4):991-4. doi: 10.1111/j.1582-4934.2006.tb00540.x.
Cutaneous melanoma is a "perfid", aggressive and hard to be treated malignant tumor in case of delayed diagnosis. However, patients still have a chance to escape progressive disease if the lesion is recognized early, when the surgical approach is curative. Dermoscopy has the important advantage of rapidity and non-invasivity in a field with (still) contradictory algorithms of diagnosis and treatment. The recognition of the elementary dermoscopic lesions enables accurate diagnosis for cutaneous melanoma. In our opinion, dermoscopy appears compulsory in the routine dermatologic examination. In vivo microscopy (dermoscopy) together with histopathology (plus or minus immunohistochemistry) seem, at present, to provide the most reliable diagnosis of melanoma.
皮肤黑色素瘤是一种“阴险的”、侵袭性强且诊断延误时难以治疗的恶性肿瘤。然而，如果病变早期被识别，此时手术治疗可治愈，患者仍有机会避免疾病进展。在诊断和治疗算法（仍）相互矛盾的领域，皮肤镜检查具有快速和非侵入性的重要优势。识别基本的皮肤镜下病变有助于准确诊断皮肤黑色素瘤。我们认为，在常规皮肤科检查中，皮肤镜检查似乎是必不可少的。目前，活体显微镜检查（皮肤镜检查）与组织病理学（加上或减去免疫组织化学）似乎能提供最可靠的黑色素瘤诊断。
