Vijayasekaran D, Kumar R Arvind, Gowrishankar N C, Nedunchelian K, Sethuraman S
Department of Pulmonology, Institute of Child Health and Hospital for Children, Egmore, Chennai, India.
Indian J Pediatr. 2006 Nov;73(11):989-93. doi: 10.1007/BF02758303.
To study the role of Mantoux and contact history in various forms of Childhood tuberculosis.
605 children registered with TB clinic of Institute of Child Health and Hospital for Children, Chennai over a 5 year period from January 2000 to October 2005 with various forms of tuberculosis were recruited in the study. Clinical examination findings, basic investigations, chest skiagrams, computerized tomography (CT) wherever warranted, sputum or gastric aspirates for AFB smear, histopathology wherever possible were analyzed.
The study showed that Mantoux positivity in various forms of tuberculosis studied is 34.7%. The positivity of Mantoux was highest in lymph node tuberculosis (53%) and the lowest with CNS tuberculosis (21.2%). Among the other forms, Mantoux positivity was 36.4% in TB abdomen, 44.4% in Skeletal TB, 30.3% in pulmonary tuberculosis. The contact positivity was 30.4% in the sample studied.
The study also reflects that the extra pulmonary forms of tuberculosis seems to be more common in the pediatric population which constituted 79.8% of the cases included in the study.
研究结核菌素试验（Mantoux试验）及接触史在儿童各型结核病中的作用。
选取2000年1月至2005年10月期间在金奈儿童健康与儿童医院结核病门诊登记的605例患各型结核病的儿童作为研究对象。分析临床检查结果、基础检查、胸部X光片、必要时的计算机断层扫描（CT）、痰或胃液抗酸杆菌涂片检查结果以及尽可能进行的组织病理学检查结果。
研究表明，在所研究的各型结核病中，结核菌素试验阳性率为34.7%。结核菌素试验阳性率在淋巴结结核中最高（53%），在中枢神经系统结核中最低（21.2%）。在其他类型中，腹部结核的结核菌素试验阳性率为36.4%，骨结核为44.4%，肺结核为30.3%。在所研究的样本中，接触史阳性率为30.4%。
该研究还反映出，肺外结核在儿童人群中似乎更为常见，在所纳入研究的病例中占79.8%。
