Yang Yu Rong, Sun Tao, Li Zhengzhi, Zhang Jianzhong, Teng Jing, Liu Xongzhou, Liu Ruiqi, Zhao Rui, Jones Malcolm K, Wang Yunhai, Wen Hao, Feng Xiaohui, Zhao Qin, Zhao Yumin, Shi Dazhong, Bartholomot Brigitte, Vuitton Dominique A, Pleydell David, Giraudoux Patrick, Ito Akira, Danson Mark F, Boufana Belchis, Craig Philip S, Williams Gail M, McManus Donald P
Ningxia Medical College, Yinchuan, Ningxia Hui Autonomous Region, China.
Bull World Health Organ. 2006 Sep;84(9):714-21. doi: 10.2471/blt.05.025718.
To determine the true community prevalence of human cystic (CE) and alveolar (AE) echinococcosis (hydatid disease) in a highly endemic region in Ningxia Hui, China, by detecting asymptomatic cases.
Using hospital records and "AE-risk" landscape patterns we selected study communities predicted to be at risk of human echinococcosis in Guyuan, Longde and Xiji counties. We conducted community surveys of 4773 individuals from 26 villages in 2002 and 2003 using questionnaire analysis, ultrasound examination and serology.
Ultrasound and serology showed a range of prevalences for AE (0-8.1%; mean 2%) and CE (0-7.4%; mean 1.6%), with the highest prevalence in Xiji (2% for CE, 2.5% for AE). There were significant differences in the prevalence of CE, AE and total echinococcosis between the three counties and villages (with multiple degrees of freedom). While hospital records showed 96% of echinococcosis cases attributable to CE, our survey showed a higher prevalence of human AE (56%) compared to CE (44%). Questionnaire analysis revealed that key risk factors for infection were age and dog ownership for both CE and AE, and Hui ethnicity and being female for AE. Drinking well-water decreased the risk for both AE and CE.
Echinococcosis continues to be a severe public health problem in this part of China because of unhygienic practices/habits and poor knowledge among the communities regarding this disease.
通过检测无症状病例，确定中国宁夏回族某高度流行地区人类囊性（CE）和泡状（AE）棘球蚴病（包虫病）的真实社区患病率。
利用医院记录和“AE风险”景观模式，我们选择了固原、隆德和西吉县预计有人类棘球蚴病风险的研究社区。我们在2002年和2003年对来自26个村庄的4773人进行了社区调查，采用问卷调查分析、超声检查和血清学检测。
超声和血清学检测显示AE患病率范围为0 - 8.1%（平均2%），CE患病率范围为0 - 7.4%（平均1.6%），西吉县患病率最高（CE为2%，AE为2.5%）。三个县和村庄之间CE、AE和总棘球蚴病患病率存在显著差异（具有多个自由度）。虽然医院记录显示96%的棘球蚴病病例归因于CE，但我们的调查显示人类AE患病率（56%）高于CE（44%）。问卷调查分析显示，感染的关键风险因素对于CE和AE都是年龄和养狗情况，对于AE还有回族身份和女性。饮用井水可降低AE和CE的风险。
由于社区卫生习惯不良/习惯以及对该疾病的了解不足，棘球蚴病在中国这一地区仍然是一个严重的公共卫生问题。
