Jánosová V, Sýkorová M, Stroffeková O, Havránek E
Univerzita Komenského v Bratislave, Farmaceutická fakulta, Katedra farmaceutickej analýzy a nukleárnej farmácie.
Ceska Slov Farm. 2006 Sep;55(5):213-8.
Pharmacopeial tests for heavy metals require comparisons between test solution's colour after addition of thioacetamide and a control solution containing a known quantity of Pb. As this test neither informs about the type of heavy metals, nor about the concentrations of each of them, there is a reason for more frequent employment of instrumental methods such as AAS and AES, as well as ICP, NAA, and X-ray fluorescence. These methods provide us with quick and exact elemental analyses of impurities, thus becoming more and more important in the quality control of drugs and medicinal plants.
药典中重金属检测要求比较加入硫代乙酰胺后供试溶液的颜色与含有已知量铅的对照溶液的颜色。由于该检测既不能告知重金属的类型，也不能告知其各自的浓度，因此有理由更频繁地使用原子吸收光谱法（AAS）、原子发射光谱法（AES）以及电感耦合等离子体质谱法（ICP）、中子活化分析法（NAA）和X射线荧光分析法等仪器方法。这些方法为我们提供了对杂质的快速准确的元素分析，从而在药品和药用植物的质量控制中变得越来越重要。
