Chastain Garvin
Boise State University, USA.
J Gen Psychol. 2006 Oct;133(4):329-35. doi: 10.3200/GENP.133.4.329-335.
Alcohol affects several neurotransmitter systems within the brain. In this article, the author describes its effects on 5 major ones: glutamate, gamma-amino-butyric acid (GABA), dopamine, serotonin, and opioid systems. The author also notes the interactions and interdependencies of these transmitters, and provides details on both immediate effects and long-term adaptations. Last, the author explains several psychopharmacological treatments for alcoholism and the effects of these treatments on transmitters, and draws conclusions.
酒精会影响大脑中的多种神经递质系统。在本文中,作者描述了其对5种主要神经递质系统的影响:谷氨酸、γ-氨基丁酸(GABA)、多巴胺、血清素和阿片类系统。作者还指出了这些递质之间的相互作用和相互依存关系,并详细介绍了即时效应和长期适应性变化。最后,作者解释了几种针对酒精成瘾的心理药理学治疗方法以及这些治疗方法对递质的影响,并得出结论。