Fiers Martijn, Ku Ka Lei, Liu Chun-Ming
Plant Research International B.V., B.U. Bioscience, P.O. Box 16, 6700 AA Wageningen, The Netherlands.
Curr Opin Plant Biol. 2007 Feb;10(1):39-43. doi: 10.1016/j.pbi.2006.11.003. Epub 2006 Nov 28.
Research in the past decade revealed that peptide ligands, also called peptide hormones, play a crucial role in intercellular communication and defense response in plants. Recent studies demonstrated that a family of plant-specific genes, CLAVATA3 (CLV3)/ENDOSPERM SURROUNDING REGION (ESR) (CLE), which has at least 31 members in Arabidopsis genome, are able to generate extracellular peptides to regulate cell division and differentiation. A hydroxyl 12-amino acid peptide derived from the conserved CLE motif of CLV3 promotes cell differentiation, whereas another CLE-derived peptide suppresses the differentiation. These peptides probably interact with membrane-bound, leucine-rich repeat receptor-like kinases (LRR-RLKs) to execute the decision between cell proliferation and differentiation.
过去十年的研究表明，肽配体，也称为肽激素，在植物的细胞间通讯和防御反应中起着至关重要的作用。最近的研究表明，一类植物特异性基因，即CLAVATA3（CLV3）/胚乳周围区域（ESR）（CLE），在拟南芥基因组中至少有31个成员，能够产生细胞外肽来调节细胞分裂和分化。源自CLV3保守CLE基序的一种含12个氨基酸的羟基肽促进细胞分化，而另一种源自CLE的肽则抑制分化。这些肽可能与膜结合的富含亮氨酸重复序列的受体样激酶（LRR-RLKs）相互作用，以决定细胞增殖和分化。
