Niessen Carien M, Yap Alpha S
Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph Stelzmannstrasse 9, 50931 Cologne.
Cell. 2006 Dec 1;127(5):875-7. doi: 10.1016/j.cell.2006.11.014.
Given the complexity of signaling pathways in the cell, it is a mystery how these pathways communicate with one other. In this issue of Cell, Wildenberg et al. (2006) reveal that the key effector molecule p120-catenin can mediate crosstalk between the Rac and Rho signaling pathways.
鉴于细胞中信号通路的复杂性,这些通路之间如何相互沟通仍是一个谜。在本期《细胞》杂志中,威尔登贝格等人(2006年)揭示关键效应分子p120连环蛋白可介导Rac和Rho信号通路之间的串扰。