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小鼠基因表达数据库(GXD):2007年更新版。

The mouse Gene Expression Database (GXD): 2007 update.

作者信息

Smith Constance M, Finger Jacqueline H, Hayamizu Terry F, McCright Ingeborg J, Eppig Janan T, Kadin James A, Richardson Joel E, Ringwald Martin

机构信息

The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.

出版信息

Nucleic Acids Res. 2007 Jan;35(Database issue):D618-23. doi: 10.1093/nar/gkl1003. Epub 2006 Nov 27.

Abstract

The Gene Expression Database (GXD) provides the scientific community with an extensive and easily searchable database of gene expression information about the mouse. Its primary emphasis is on developmental studies. By integrating different types of expression data, GXD aims to provide comprehensive information about expression patterns of transcripts and proteins in wild-type and mutant mice. Integration with the other Mouse Genome Informatics (MGI) databases places the gene expression information in the context of genetic, sequence, functional and phenotypic information, enabling valuable insights into the molecular biology that underlies developmental and disease processes. In recent years the utility of GXD has been greatly enhanced by a large increase in data content, obtained from the literature and provided by researchers doing large-scale in situ and cDNA screens. In addition, we have continued to refine our query and display features to make it easier for users to interrogate the data. GXD is available through the MGI web site at http://www.informatics.jax.org/ or directly at http://www.informatics.jax.org/menus/expression_menu.shtml.

摘要

基因表达数据库(GXD)为科学界提供了一个关于小鼠基因表达信息的广泛且易于搜索的数据库。其主要重点是发育研究。通过整合不同类型的表达数据,GXD旨在提供关于野生型和突变型小鼠中转录本和蛋白质表达模式的全面信息。与其他小鼠基因组信息学(MGI)数据库的整合将基因表达信息置于遗传、序列、功能和表型信息的背景下,从而能够深入了解发育和疾病过程背后的分子生物学。近年来,通过大幅增加从文献中获取并由进行大规模原位和cDNA筛选的研究人员提供的数据内容,GXD的实用性得到了极大提升。此外,我们不断完善查询和显示功能,以便用户更轻松地查询数据。可通过MGI网站http://www.informatics.jax.org/ 或直接通过http://www.informatics.jax.org/menus/expression_menu.shtml访问GXD。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0299/1781100/af42ff05bd09/gkl1003f1.jpg

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