Ando Yukio
Department of Diagnostic Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-0811.
Rinsho Byori. 2006 Oct;54(10):1038-43.
Pathologic informatics is an analysis of mechanism of pathogenesis using various medical information. Biologic reactions by many reactants are studied on molecules, cells, organs, and individuals by using various methods. Themes of our laboratory are as follows: 1) to analyze of the pathogenesis of various diseases by using novel diagnostic methods, 2) to elucidate amyloid formation mechanism in amyloidosis and to develop novel therapies, 3) to develop the methods for tests and diagnosis for DIC, 4) to study on activation mechanism of ribosomal proteins in the tissues by the blood cell function, 5) to study on the expression and suppression of neogenesis of blood vessels by physical invasion in the organ failure, and 6) to develop the diagnostic methods for autonomic dysfunction and to analyze the pathogenesis.
病理信息学是利用各种医学信息对发病机制进行分析。通过各种方法,在分子、细胞、器官和个体层面研究多种反应物的生物学反应。我们实验室的研究主题如下:1)利用新型诊断方法分析各种疾病的发病机制;2)阐明淀粉样变性中淀粉样蛋白的形成机制并开发新疗法;3)开发弥散性血管内凝血(DIC)的检测和诊断方法;4)研究血细胞功能对组织中核糖体蛋白的激活机制;5)研究器官衰竭时物理侵袭对血管新生的表达和抑制作用;6)开发自主神经功能障碍的诊断方法并分析其发病机制。