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小儿脑干梗死与基底动脉开窗畸形之间的因果关系?

Causality of pediatric brainstem infarction and basilar artery fenestration?

作者信息

Kloska Stephan P, Schlegel Philip M, Sträter Ronald, Niederstadt Thomas U

机构信息

Department of Clinical Radiology, University of Muenster, Muenster, Germany.

出版信息

Pediatr Neurol. 2006 Dec;35(6):436-8. doi: 10.1016/j.pediatrneurol.2006.06.013.

Abstract

Pediatric arterial thromboembolic stroke is an uncommon condition and rarely is reported to be associated with a cerebral artery fenestration. This clinical report discusses the case of a child with brainstem infarction and basilar artery fenestration. A cardiac source of thromboembolic events could be excluded; however, detailed coagulation analysis revealed in addition an apoliopoprotein(a) size polymorphism. Because we assume that the two concurrent pathologies in combination caused the arterial thromboembolic stroke, the evaluation of all potential triggers including vascular anomalies and coagulation disorders should be considered in unexplained pediatric infarction.

摘要

小儿动脉血栓栓塞性卒中是一种罕见病症,很少有报道称其与脑动脉开窗有关。本临床报告讨论了一名患有脑干梗死和基底动脉开窗的儿童病例。可以排除血栓栓塞事件的心脏来源;然而,详细的凝血分析还发现了载脂蛋白(a)大小多态性。由于我们认为这两种并发病症共同导致了动脉血栓栓塞性卒中,因此在不明原因的小儿梗死中,应考虑评估所有潜在诱因,包括血管异常和凝血障碍。

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