Rothkopf Michael M
South Mountain Medical Consultants, West Orange, New Jersey 07052, USA.
Surg Obes Relat Dis. 2006 Nov-Dec;2(6):656-60. doi: 10.1016/j.soard.2006.08.015.
Significant deficiencies of both fat- and water-soluble vitamins have been reported to occur after malabsorptive bariatric surgery. However, despite the potential for neurologic manifestations of such deficiencies, few cases of central neurologic dysfunction have been reported. Our group previously reported reversible neurologic dysfunction as an unusual manifestation of vitamin deficiency in a postjejunoileostomy patient. We report on a second case of reversible neurologic dysfunction associated with severe, prolonged vitamin deficiency many years after jejunoileostomy. Neurologic function returned to normal with vitamin repletion. Patients who have undergone malabsorptive surgery are at risk of late metabolic complications and should be closely monitored.
据报道,在进行导致吸收不良的减肥手术后,脂溶性维生素和水溶性维生素均出现明显缺乏。然而,尽管这些维生素缺乏可能会出现神经学表现,但中枢神经功能障碍的病例报道却很少。我们团队之前曾报道过,空肠回肠造口术后患者出现维生素缺乏的罕见表现——可逆性神经功能障碍。我们在此报告第二例与空肠回肠造口术后多年严重、长期维生素缺乏相关的可逆性神经功能障碍病例。补充维生素后神经功能恢复正常。接受过吸收不良手术的患者有发生晚期代谢并发症的风险,应密切监测。