脑电图睡眠的遗传决定因素：对异地生活双胞胎的一项研究。

Genetic determinants of EEG sleep: a study in twins living apart.

作者信息

Linkowski P, Kerkhofs M, Hauspie R, Mendlewicz J

机构信息

Department of Psychiatry, Hôpital Erasme, Université Libre de Bruxelles Belgium.

出版信息

Electroencephalogr Clin Neurophysiol. 1991 Aug;79(2):114-8. doi: 10.1016/0013-4694(91)90048-9.

DOI:10.1016/0013-4694(91)90048-9

PMID:1713824

Abstract

In order to investigate the genetic components of sleep and, in particular, of REM sleep, we performed 3 consecutive all-night EEG recordings in 26 pairs of normal male twins living apart (11 monozygotic and 15 dizygotic). Our results indicate that in man non-genetic rather than genetic influences substantially determine variance in stage REM, in contrast to stages 2, 4 and to delta sleep. In this sample of male twins, waking measures also showed a significant genetic component.

摘要

为了研究睡眠尤其是快速眼动睡眠的遗传成分，我们对26对分开生活的正常男性双胞胎（11对同卵双胞胎和15对异卵双胞胎）进行了连续3次整夜脑电图记录。我们的结果表明，与2期、4期睡眠及慢波睡眠相反，在人类中，非遗传因素而非遗传因素在很大程度上决定了快速眼动睡眠阶段的差异。在这个男性双胞胎样本中，清醒状态的测量结果也显示出显著的遗传成分。