Yanagita Masahiko, Willcox Bradley J, Masaki Kamal H, Chen Randi, He Qimei, Rodriguez Beatriz L, Ueshima Hirotsugu, Curb J David
Fukui Prefectural University, Fukui, Japan.
Am J Geriatr Psychiatry. 2006 Dec;14(12):1060-8. doi: 10.1097/01.JGP.0000224364.70515.12.
The objective of this study was to examine the relation of physical performance measures with depressive symptoms in older men.
A cross-sectional, multivariate comparison of several measures of upper- and lower-extremity performance and their relation with depressive symptoms was performed in 2,856 older Japanese American men, aged 71-93 years, who participated in the fourth examination of the Honolulu Heart Program. Depressive symptoms were measured using an 11-item version of Center for Epidemiologic Studies Depression (CES-D) Scale. A score of at least 9 (from a maximum score of 33) is considered clinically significant. Timed functional performance tests, including walking and repeated chair stands, were used to assess lower-extremity performance; handgrip strength was used as an indicator of upper-extremity performance.
Two hundred eighty-three participants (9.9%) had a score of 9 or greater on the 11-question CES-D Scale and were considered to be at high risk for depression. Time to walk 10 feet and time to complete five chair stands were significantly longer in those with depressive symptoms, whereas handgrip strength was significantly lower. Only the association of gait speed (time to walk 10 feet) and depressive symptoms remained significant when all physical performance measures were simultaneously included in a multivariate analysis.
These results demonstrate physical performance measures, particularly gait speed, may be important potential correlates of depression in community-dwelling older men.
本研究的目的是探讨老年男性身体机能指标与抑郁症状之间的关系。
对2856名年龄在71 - 93岁的日裔美国老年男性进行了横断面、多变量比较,这些男性参加了檀香山心脏项目的第四次检查,比较了上下肢机能的多项指标及其与抑郁症状的关系。抑郁症状采用流行病学研究中心抑郁量表(CES - D)的11项版本进行测量。至少9分(满分33分)的分数被认为具有临床意义。采用定时功能表现测试,包括步行和重复起坐测试,来评估下肢机能;握力作为上肢机能的指标。
283名参与者(9.9%)在11项CES - D量表上的得分达到或超过9分,被认为有较高的抑郁风险。有抑郁症状的参与者步行10英尺的时间和完成5次起坐的时间明显更长,而握力明显更低。当所有身体机能指标同时纳入多变量分析时,只有步态速度(步行10英尺的时间)与抑郁症状的关联仍然显著。
这些结果表明,身体机能指标,特别是步态速度,可能是社区居住老年男性抑郁的重要潜在相关因素。