油菜素甾醇信号传导：细胞表面类固醇激素信号传导的范例。

Brassinosteroid signaling: a paradigm for steroid hormone signaling from the cell surface.

作者信息

Belkhadir Youssef, Chory Joanne

机构信息

Plant Biology Laboratory and Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

出版信息

Science. 2006 Dec 1;314(5804):1410-1. doi: 10.1126/science.1134040.

DOI:10.1126/science.1134040

PMID:17138891

Abstract

Plants use the coordinated action of several small-molecule hormones to grow and develop optimally in response to a changing environment. Among these hormones are the brassinosteroids (BRs), the polyhydroxylated steroid hormones of plants. BRs bind a small family of leucine-rich repeat receptor kinases at the cell surface, thereby initiating an intracellular signal transduction cascade that results in the altered expression of hundreds of genes.

摘要

植物利用几种小分子激素的协同作用，以在不断变化的环境中实现最佳生长和发育。这些激素中包括油菜素甾体类（BRs），即植物的多羟基甾体激素。BRs在细胞表面与一小类富含亮氨酸重复序列的受体激酶结合，从而启动细胞内信号转导级联反应，导致数百个基因的表达发生改变。