School of Biological Sciences, University of Western Australia, Perth, WA 6009, Australia.
Int J Mol Sci. 2020 Dec 30;22(1):313. doi: 10.3390/ijms22010313.
Among the oilseeds, canola () is the most economically significant globally. However, its production can be limited by blackleg disease, caused by the fungal pathogen . The deployment of resistance genes has been implemented as one of the key strategies to manage the disease. Genetic resistance against blackleg comes in two forms: qualitative resistance, controlled by a single, major resistance gene ( gene), and quantitative resistance (QR), controlled by numerous, small effect loci. -gene-mediated blackleg resistance has been extensively studied, wherein several genomic regions harbouring genes against have been identified and three of these genes were cloned. These studies advance our understanding of the mechanism of gene and pathogen avirulence () gene interaction. Notably, these studies revealed a more complex interaction than originally thought. Advances in genomics help unravel these complexities, providing insights into the genes and genetic factors towards improving blackleg resistance. Here, we aim to discuss the existing -gene-mediated resistance, make a summary of candidate genes against the disease, and emphasise the role of players involved in the pathogenicity and resistance. The comprehensive result will allow breeders to improve resistance to thereby increasing yield.
在油籽中，油菜（）是全球最重要的经济作物。然而，其生产可能受到黑胫病的限制，这种疾病是由真菌病原体引起的。部署抗性基因已成为管理该疾病的关键策略之一。对黑胫病的遗传抗性有两种形式：由单个主要抗性基因（）控制的定性抗性，和由多个小效应位点控制的数量抗性（QR）。-基因介导的黑胫病抗性已得到广泛研究，其中已经鉴定出几个含有针对的基因的基因组区域，并且克隆了其中三个基因。这些研究增进了我们对基因和病原菌无毒基因（）相互作用机制的理解。值得注意的是，这些研究揭示了比最初想象的更为复杂的相互作用。基因组学的进步有助于揭示这些复杂性，为提高黑胫病抗性提供了有关基因和遗传因素的见解。在这里，我们旨在讨论现有的-基因介导的抗性，总结针对该疾病的候选基因，并强调参与致病性和抗性的参与者的作用。全面的结果将使育种者能够提高对的抗性，从而提高产量。
