Vignon F, Aubry J F, Tanter M, Margoum A, Fink M
Laboratoire Ondes et Acoustique, ESPCI, Université Paris VII, C.N.R.S U.M.R.7587, 10 rue Vauquelin, 75231 Paris, France.
J Acoust Soc Am. 2006 Nov;120(5 Pt 1):2737-45. doi: 10.1121/1.2354073.
Ultrasonic brain imaging remains difficult and limited because of the strong aberrating effects of the skull (absorption, diffusion and refraction of ultrasounds): high resolution transcranial imaging would require adaptive focusing techniques in order to correct the defocusing effect of the skull. In this paper, a noninvasive brain imaging device is presented. It is made of two identical linear arrays of 128 transducers located on each side of the skull. It is possible to separate the respective influence of the two bone windows on the path of an ultrasonic wave propagating from one array to the other, and thus estimate at each frequency the attenuation and phase shift locally induced by each bone window. The information obtained on attenuation and phase is used to correct the wave fronts that have to be sent through the skull in order to obtain a good focusing inside the skull. Compared to uncorrected wave fronts, the spatial shift of the focal spot is corrected, the width of the focal spot is reduced, and the sidelobes level is decreased up to 17 dB. Transcranial images of a phantom are presented and exhibit the improvement in image quality provided by this new noninvasive adaptive focusing method.
由于颅骨对超声波具有强烈的像差效应(超声波的吸收、散射和折射),超声脑成像仍然困难且受限:高分辨率经颅成像需要自适应聚焦技术来校正颅骨的散焦效应。本文介绍了一种非侵入性脑成像设备。它由位于颅骨两侧的两个相同的128个换能器线性阵列组成。可以分离两个骨窗对从一个阵列传播到另一个阵列的超声波路径的各自影响,从而在每个频率下估计每个骨窗局部引起的衰减和相移。通过衰减和相位获得的信息用于校正必须穿过颅骨发送的波前,以便在颅骨内实现良好聚焦。与未校正的波前相比,焦点的空间偏移得到校正,焦点宽度减小,旁瓣电平降低高达17 dB。给出了体模的经颅图像,展示了这种新的非侵入性自适应聚焦方法所带来的图像质量提升。