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拆除活动与儿童血铅水平之间的关联。

The association between demolition activity and children's blood lead levels.

作者信息

Rabito F A, Iqbal S, Shorter C F, Osman P, Philips P E, Langlois E, White L E

机构信息

Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA.

出版信息

Environ Res. 2007 Mar;103(3):345-51. doi: 10.1016/j.envres.2006.09.011. Epub 2006 Nov 30.

Abstract

Urban renewal efforts are a priority for many American cities. As efforts to reconstitute urban centers increase, the demolition of old, deteriorated structures has accelerated. Recent studies have identified demolitions as a potential source of environmental lead exposure. We conducted a study examining the relationship between demolition activity and blood lead levels of children residing in neighborhoods where demolition activity occurred. A retrospective cohort study was conducted in St. Louis City, Missouri. The study period was January 1, 2002 to December 31, 2002. Data were obtained from the Missouri Childhood Lead Poisoning Prevention Program's (CLPPP) lead surveillance system and St. Louis Demolition Permit Database. Children were considered exposed to a demolition if they had a blood lead test within 45 days of any demolition on a census block. Exposure was classified as both a dichotomous (yes/no) and a categorical (none/one/multiple) variable and was analyzed separately. Linear regression models were developed to determine effects of demolitions on blood lead levels. A total of 1196 children 6-72 months of age living in 395 census blocks were included. 314 (26.3%) were exposed and 882 (73.7%) were unexposed to a demolition. In an adjusted model, exposure to multiple demolitions was found to have significant effects on children blood lead levels (coefficient=0.281; 95% CI=0.069, 0.493; P-value=0.010). Age of the child, race, and age of housing where children's resided were also significant predictors. This study suggests that multiple demolitions within a census block may significantly increase children's blood lead levels. The findings may be useful to municipal planners in older cities where demolitions are being used as an urban renewal tool.

摘要

城市更新工作是许多美国城市的优先事项。随着重建城市中心的努力不断增加,老旧、破败建筑的拆除速度加快。最近的研究已将拆除工作确定为环境铅暴露的一个潜在来源。我们开展了一项研究,考察拆除活动与居住在拆除活动发生社区的儿童血铅水平之间的关系。在密苏里州圣路易斯市进行了一项回顾性队列研究。研究期间为2002年1月1日至2002年12月31日。数据取自密苏里州儿童铅中毒预防项目(CLPPP)的铅监测系统和圣路易斯拆除许可数据库。如果儿童在人口普查街区的任何拆除活动后45天内进行了血铅检测,则被视为暴露于拆除活动。暴露被分类为二分变量(是/否)和分类变量(无/一次/多次),并分别进行分析。建立线性回归模型以确定拆除活动对血铅水平的影响。共纳入了居住在395个人口普查街区的1196名6至72个月大的儿童。314名(26.3%)暴露于拆除活动,882名(73.7%)未暴露于拆除活动。在一个校正模型中,发现暴露于多次拆除活动对儿童血铅水平有显著影响(系数=0.281;95%置信区间=0.069,0.493;P值=0.010)。儿童年龄、种族以及儿童居住房屋的房龄也是显著的预测因素。这项研究表明,人口普查街区内的多次拆除活动可能会显著提高儿童的血铅水平。这些发现可能对将拆除作为城市更新工具的老城市的市政规划者有用。

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